Creative Medical Technology (CELZ)

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Creative Medical Technology Holdings, Inc. is a biotechnology company developing regenerative medicine and cell-based therapies for conditions with significant unmet medical needs. The company is commercial-stage but remains heavily focused on clinical development, intellectual property, and the translation of stem cell and immune-cell science into potential treatments across several therapeutic areas.

Its programs span immunology, endocrinology, urology, neurology, orthopedics, and reproductive medicine. Creative Medical’s pipeline includes ImmCelz, also known as CELZ-100, a personalized immune therapy platform designed to modify a patient’s immune cells with the aim of improving therapeutic response. The company is also advancing AlloStem, or CELZ-201-DDT, and CREATE-1, a program targeting recent-onset Type 1 diabetes.

Beyond diabetes and immune therapy, Creative Medical has developed regenerative approaches for spine-related pain, sexual health, infertility, and organ-related disorders. Its portfolio includes AlloStemSpine for lower back pain, Alova for infertility linked to premature ovarian failure, and other programs such as OvaStem, CaverStem, FemCelz, and StemSpine. These assets reflect the company’s strategy of building a broad platform around cellular repair, immune modulation, and tissue regeneration.

For investors, CELZ represents exposure to an early-stage regenerative medicine business where valuation is closely tied to clinical progress, regulatory outcomes, financing needs, and the strength of its patent estate. Like many small biotechnology companies, Creative Medical carries high development risk, but its appeal lies in the potential breadth of its technology across multiple medical specialties.

1.15USD
1.41 USD
+0.48(+71.92%)
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Last updated

Market Cap
$4,281,425
P/E
P/FCF
P/S
1,427.14
Enterprise Value
-$1,441,751
Sector
Materials
Industry
Biological Products, Except Diagnostic Substances
Address
211 E. OSBORN RD., PHOENIX, AZ, 85012
Market Cap
$4,281,425
Enterprise Value
-$1,441,751
P/E
P/B
0.7
P/S
1,427.14
EV / EBITDA
0.25
EV / Sales
-480.58
EPS
-0.89
Dividend Yield
0%
P/FCF
P/CF
Free Cash Flow
ROE
-94.31%
ROA
-89.46%
Debt / Equity
0
Current Ratio
19.69
Quick Ratio
19.29
Cash
18.6
Avg Volume
$6,814,013
Fundamentals Snapshot Price
0.66

Income Statement

Line Item2025 Q42024 Q42023 Q42022 Q42021 Q4
Revenue6K11K9K88.6K87.75K
Cost of revenue2.19K4.4K3.6K28.49K47.95K
Gross profit3.81K6.6K5.4K60.11K39.81K
Operating income-6.14M-5.74M-5.62M-10.24M-3.13M
EBITDA-6.02M-5.63M-5.53M-10.15M-3.03M
Net income-6M-5.49M-5.29M-10.14M19.21M
Interest expense-4.28M
Other operating expenses00000
Total operating expenses6.15M5.75M5.63M10.3M3.17M
Basic EPS-2.52-3.71-3.76-9.2873.7
Diluted EPS-2.52-3.71-3.76-9.2856.1

Balance Sheet

Line Item2025 Q42024 Q42023 Q42022 Q42021 Q4
Total assets7.81M6.67M10.72M19.19M11.27M
Total liabilities284.88K327.64K371.39K3.32M1.05M
Total equity7.52M6.34M10.34M15.86M10.22M
Cash & equivalents7.21M5.94M3.47M8.32M10.72M
Current assets7.4M6.14M10.27M18.75M10.74M
Current liabilities284.88K327.64K371.39K3.32M1.05M
Accounts payable270.69K273.53K317.28K3.27M1.01M
Receivables52.08K0002.49K
Inventories2.19K6.59K10.19K10.87K

Cash Flow

Line Item2025 Q42024 Q42023 Q42022 Q42021 Q4
Operating cash flow-5.86M-5.3M-8.03M-7.8M-2.22M
Investing cash flow-50.5K6.32M3.45M-10.08M0
Financing cash flow7.17M1.45M-270.95K15.47M12.84M
Change in cash1.27M2.47M-4.85M-2.4M10.63M
Net income-6M-5.49M-5.29M-10.14M19.21M
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edgar index10-Q — CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.View Filing
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edgar indexEFFECT — CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.View Filing
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eight k text8-K — 8-KView Filing
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edgar index8-K — CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.View Filing
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edgar index8-K — CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.View Filing
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edgar indexCORRESP — CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.View Filing
edgar indexUPLOAD — CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.View Filing
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edgar index424B5 — CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.View Filing
edgar index8-K — CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.View Filing
edgar indexPRER14A — CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.View Filing
edgar indexEFFECT — CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.View Filing
edgar indexUPLOAD — CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.View Filing