Polyrizon (PLRZ)
Nasdaq Market Open
Polyrizon Ltd. is a clinical-stage biotechnology company developing intranasal gel technologies designed to act as a protective barrier in the nasal cavity. Its work is based on the idea that the nose is a primary entry point for many airborne biological and environmental threats, including respiratory viruses, allergens, and other harmful particles. Rather than treating infection after it has taken hold, Polyrizon focuses on preventative products intended to reduce exposure at the point of entry.
The company’s development programs centre on proprietary platforms known as Capture & Contain and Trap & Target. These technologies are designed to create a physical and functional barrier that can capture, retain, or otherwise limit contact between harmful agents and nasal tissue. Potential applications include protection against influenza, certain COVID-19 variants, allergens, and toxins, although the company remains in the clinical development stage and its products are subject to regulatory review and commercial validation.
Polyrizon operates in a healthcare market shaped by demand for non-invasive, easy-to-administer preventative solutions. Intranasal products may be attractive because they can be used without injections or complex medical procedures and could complement vaccines, masks, allergy treatments, or other protective measures. As a biotech company, its prospects depend on clinical data, safety results, regulatory approvals, manufacturing capability, intellectual property protection, and the ability to secure commercial partnerships or distribution channels.
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Polyrizon Ltd. Files Annual Report on Form 20-F for the Fiscal Year Ended December 31, 2025
Polyrizon Completes FDA Pre-Submission Meeting for PL-14 Allergy Blocker Nasal Spray
Polyrizon Initiates Preclinical Studies for Intranasal Naloxone Targeting Opioid Overdose Based on Its Innovative T&T Platform
Polyrizon Announces Filing of Divisional Patent Application for Its Innovative Trap & Target™ (T&T) Intranasal Drug Delivery Platform
Polyrizon Enters into GMP Manufacturing Agreement for CTM Supply of its PL-14 Allergy Blocker in Preparation for Planned 2025 Clinical Trial
Income Statement
| Line Item | 2025 Q4 | 2024 Q4 |
|---|---|---|
| Revenue | — | — |
| Gross profit | — | — |
| Operating income | — | — |
| EBITDA | 0 | 0 |
| Net income | — | — |
| Basic EPS | — | — |
| Diluted EPS | — | — |
Balance Sheet
| Line Item | 2025 Q4 | 2024 Q4 |
|---|---|---|
| Total assets | 21.44M | 5.55M |
| Total liabilities | 443K | 261K |
| Total equity | 20.99M | 5.29M |
| Cash & equivalents | 1.31M | 2.55M |
| Current assets | 12.86M | 2.65M |
| Current liabilities | 443K | 261K |
Cash Flow
| Line Item | 2025 Q4 | 2024 Q4 |
|---|---|---|
| Operating cash flow | — | — |
| Investing cash flow | — | — |
| Financing cash flow | — | — |
| Change in cash | — | — |
| Kind | Filing | Date | Link |
|---|---|---|---|
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | EFFECT — Polyrizon Ltd. | View Filing | |
| edgar index | CORRESP — Polyrizon Ltd. | View Filing | |
| edgar index | UPLOAD — Polyrizon Ltd. | View Filing | |
| edgar index | SCHEDULE 13G — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | F-1 — Polyrizon Ltd. | View Filing | |
| edgar index | D — Polyrizon Ltd. | View Filing | |
| edgar index | 424B5 — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | 4 — Polyrizon Ltd. | View Filing | |
| edgar index | 4 — Polyrizon Ltd. | View Filing | |
| edgar index | 4 — Polyrizon Ltd. | View Filing | |
| form 4 | Form 4 — Adler Oz | View Filing | |
| form 4 | Form 4 — Carmel Liron | View Filing | |
| form 4 | Form 4 — Izraeli Tomer | View Filing | |
| edgar index | 20-F/A — Polyrizon Ltd. | View Filing | |
| edgar index | 20-F — Polyrizon Ltd. | View Filing | |
| edgar index | 3 — Polyrizon Ltd. | View Filing | |
| edgar index | 3 — Polyrizon Ltd. | View Filing | |
| edgar index | 3 — Polyrizon Ltd. | View Filing | |
| edgar index | 3 — Polyrizon Ltd. | View Filing | |
| edgar index | 3 — Polyrizon Ltd. | View Filing | |
| edgar index | 3 — Polyrizon Ltd. | View Filing | |
| edgar index | 3 — Polyrizon Ltd. | View Filing | |
| edgar index | 3 — Polyrizon Ltd. | View Filing | |
| edgar index | 3 — Polyrizon Ltd. | View Filing | |
| form 3 | Form 3 — BenYosef Nir | View Filing | |
| form 3 | Form 3 — BenYosef Nir | View Filing | |
| form 3 | Form 3 — BenYosef Nir | View Filing | |
| form 3 | Form 3 — Izraeli Tomer | View Filing | |
| form 3 | Form 3 — Izraeli Tomer | View Filing | |
| form 3 | Form 3 — Izraeli Tomer | View Filing | |
| form 3 | Form 3 — Izraeli Tomer | View Filing | |
| form 3 | Form 3 — Izraeli Tomer | View Filing | |
| form 3 | Form 3 — Adler Oz | View Filing | |
| form 3 | Form 3 — Adler Oz | View Filing | |
| form 3 | Form 3 — Turgeman Tidhar | View Filing | |
| form 3 | Form 3 — Turgeman Tidhar | View Filing | |
| form 3 | Form 3 — Turgeman Tidhar | View Filing | |
| form 3 | Form 3 — Turgeman Tidhar | View Filing | |
| form 3 | Form 3 — Turgeman Tidhar | View Filing | |
| form 3 | Form 3 — Carmel Liron | View Filing | |
| form 3 | Form 3 — Carmel Liron | View Filing | |
| form 3 | Form 3 — Vinokur Yehonatan Zalman | View Filing | |
| form 3 | Form 3 — Vinokur Yehonatan Zalman | View Filing | |
| form 3 | Form 3 — Ron Eyal S | View Filing | |
| form 3 | Form 3 — Ron Eyal S | View Filing | |
| form 3 | Form 3 — Ron Eyal S | View Filing | |
| form 3 | Form 3 — Ron Eyal S | View Filing | |
| form 3 | Form 3 — Sidi Liat | View Filing | |
| form 3 | Form 3 — Sidi Liat | View Filing | |
| form 3 | Form 3 — Itzhaik Asaf | View Filing | |
| form 3 | Form 3 — Itzhaik Asaf | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | SCHEDULE 13G — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | SCHEDULE 13G/A — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | SCHEDULE 13G — Polyrizon Ltd. | View Filing | |
| edgar index | SCHEDULE 13G — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | 424B5 — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing | |
| edgar index | 6-K — Polyrizon Ltd. | View Filing |