MeiraGTx Holdings (MGTX)

Nasdaq Market Open

MeiraGTx Holdings plc is a clinical-stage genetic medicines company developing gene-based therapies for serious disorders where existing treatment options are limited. The company focuses on targeted delivery of therapeutic genes and gene-regulation technologies, with programmes spanning ophthalmology, neurodegenerative disease and salivary gland disorders. Its areas of development include radiation-induced xerostomia, Parkinson’s disease and AIPL1-associated retinal dystrophy, among other inherited or acquired conditions.

A defining feature of MeiraGTx is its vertically integrated operating model. The company has built internal capabilities across vector design, process development, GMP viral vector manufacturing, plasmid production and quality control. This infrastructure is intended to give the business greater control over product quality, scale-up and supply as candidates progress from investigational studies toward potential commercial use.

MeiraGTx also works with proprietary technology platforms designed to improve the performance and safety profile of genetic medicines. Its viral vector engineering efforts aim to optimise delivery to specific tissues, while its riboswitch-based gene regulation platform is designed to control the level of therapeutic protein expression after administration. These tools may help reduce dosing requirements or improve the therapeutic window of gene therapies.

The company operates across the United States, the United Kingdom and the European Union, giving it access to major research, regulatory and clinical development markets. As a listed biotechnology stock, MeiraGTx is tied to the progress of its clinical pipeline, manufacturing execution, regulatory milestones and the broader investor appetite for genetic medicine companies.

9.12 USD
−0.44 (-4.60%)

Last updated

Market Cap
886.27M
P/E
P/FCF
213.3
P/S
11.11
Enterprise Value
889.43M
Sector
Health Care
Industry
Biological Products, Except Diagnostic Substances
Address
655 THIRD AVENUE, NEW YORK, NY, 10017
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05 Aug 2025, 18:00 PM
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MeiraGTx to Participate in Upcoming Investor Conferences

24 Apr 2024, 21:30 PM
GlobeNewswire Inc.

MeiraGTx Announces Oral Presentation at the 2024 American Academy of Oral Medicine (AAOM) Annual Conference

18 Apr 2024, 21:30 PM
GlobeNewswire Inc.

MeiraGTx Reports Fourth Quarter and Full Year 2023 Financial and Operational Results and Recent Business Updates

14 Mar 2024, 12:30 PM
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Praxis Precision Medicines, Inc. (PRAX) Reports Q4 Loss, Tops Revenue Estimates

05 Mar 2024, 13:10 PM
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MeiraGTx (MGTX): Strong Industry, Solid Earnings Estimate Revisions

10 Jan 2024, 13:49 PM
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Wall Street Analysts Believe MeiraGTx Holdings PLC (MGTX) Could Rally 221.78%: Here's is How to Trade

25 Dec 2023, 14:55 PM
GlobeNewswire Inc.

MeiraGTx Announces Asset Purchase Agreement Involving its AAV-RPGR Collaboration for up to $415 million

21 Dec 2023, 12:00 PM
GlobeNewswire Inc.

MeiraGTx to Participate in Upcoming Investor Conferences

21 Nov 2023, 21:30 PM
GlobeNewswire Inc.

MeiraGTx Announces $30 Million Strategic Investment from Sanofi; Company Pursuing Multiple Additional Strategic Opportunities

30 Oct 2023, 11:30 AM
MarketWatch

MeiraGTx shares jump as Sanofi invests in gene therapy

30 Oct 2023, 11:28 AM
GlobeNewswire Inc.

MeiraGTx Announces an Oral Presentation and Eight Posters at the European Society of Gene and Cell Therapy (ESGCT) 2023 Annual Congress

24 Oct 2023, 13:30 PM
Zacks Investment Research

MeiraGTx Holdings PLC (MGTX) Reports Q2 Loss, Misses Revenue Estimates

10 Aug 2023, 14:15 PM
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Guardant Health (GH) Reports Q2 Loss, Tops Revenue Estimates

03 Aug 2023, 22:45 PM
GlobeNewswire Inc.

MeiraGTx Announces Poster Presentation at the 2023 American Society of Gene and Cell Therapy (ASGCT) Spotlight on Immuno-Oncology

01 Aug 2023, 14:10 PM
GlobeNewswire Inc.

MeiraGTx Announces its Wholly-Owned Gene Therapy Manufacturing Facility in Shannon, Ireland has Received Commercial MIA Authorization for QC Testing

19 Jul 2023, 13:30 PM
GlobeNewswire Inc.

MeiraGTx Announces Positive Clinical Data from the AQUAx Phase 1 Clinical Study of AAV2-hAQP1 for the Treatment of Grade 2/3 Radiation-Induced Xerostomia

27 Jun 2023, 12:30 PM
GlobeNewswire Inc.

MeiraGTx to Present 12-month Data from All Cohorts of the Completed Phase 1 AQUAx Clinical Study and an Update on the Company’s Recently Initiated Phase 2 Study of AAV-hAQP1 for the Treatment of Grade 2/3 Radiation-Induced Xerostomia on Tuesday, June 27, 2023

22 Jun 2023, 21:01 PM
Zacks Investment Research

Does MeiraGTx Holdings PLC (MGTX) Have the Potential to Rally 320.9% as Wall Street Analysts Expect?

02 Jun 2023, 14:55 PM
Market Cap
886.27M
Enterprise Value
889.43M
P/E
P/B
-15.25
P/S
11.11
EV / EBITDA
-9.59
EV / Sales
11.15
EPS
-1.3
Dividend Yield
0%
P/FCF
213.3
P/CF
107.05
Free Cash Flow
4.16M
ROE
207.35%
ROA
-49.27%
Debt / Equity
-1.29
Current Ratio
0.55
Quick Ratio
0.55
Cash
0.41
Avg Volume
747.79K
Fundamentals Snapshot Price
9.57

Income Statement

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Revenue 293K 75.36M 410K 3.69M 1.93M
Gross profit 293K 75.36M 410K 3.69M 1.93M
Operating income -40.82M 26.47M -46.05M -44.79M -41.6M
EBITDA -37.81M 29.59M -42.9M -41.6M -38.52M
Net income -46.31M 15.09M -50.51M -38.8M -39.98M
Basic EPS -0.57 0.19 -0.62 -0.48 -0.51
Diluted EPS -0.57 0.19 -0.62 -0.48 -0.51

Balance Sheet

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Total assets 244.66M 244.43M 189.47M 198.72M 224.01M
Total liabilities 302.79M 250.22M 230.03M 195.76M 190.92M
Total equity -58.13M -5.79M -40.56M 2.96M 33.1M
Cash & equivalents 71.54M 65.93M 14.84M 32.17M 66.52M
Current assets 96.2M 91.76M 34.17M 47.08M 79.89M
Current liabilities 176.13M 122.56M 152.92M 53.44M 52.37M

Cash Flow

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Operating cash flow 17.81M 46.63M -12.22M -43.95M -36.83M
Investing cash flow -2.26M -1.09M -547K -761K -1.71M
Financing cash flow -10.11M 5.33M -219K 5.45M 1.71M
Change in cash 5.44M 50.87M -12.98M -39.26M -36.83M
Kind Filing Date Link
edgar index 4 — MeiraGTx Holdings plc View Filing
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edgar index 144 — MeiraGTx Holdings plc View Filing
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eight k text 8-K — 8-K View Filing
edgar index 4 — MeiraGTx Holdings plc View Filing
edgar index 144 — MeiraGTx Holdings plc View Filing
edgar index 4 — MeiraGTx Holdings plc View Filing
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form 4 Form 4 — PERCEPTIVE ADVISORS LLC View Filing
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edgar index 8-K — MeiraGTx Holdings plc View Filing
edgar index 8-K — MeiraGTx Holdings plc View Filing
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edgar index 424B5 — MeiraGTx Holdings plc View Filing
eight k text 8-K — 8-K View Filing
eight k text 8-K — 8-K View Filing
eight k text 8-K — 8-K View Filing
edgar index 4 — MeiraGTx Holdings plc View Filing
edgar index 144 — MeiraGTx Holdings plc View Filing
form 4 Form 4 — Naylor Stuart View Filing
edgar index 10-K — MeiraGTx Holdings plc View Filing
edgar index 8-K — MeiraGTx Holdings plc View Filing
eight k text 8-K — 8-K View Filing
form 4 Form 4 — EDELMAN JOSEPH View Filing
form 4 Form 4 — PERCEPTIVE LIFE SCIENCES MASTER FUND LTD View Filing
form 4 Form 4 — PERCEPTIVE ADVISORS LLC View Filing
form 4 Form 4 — EDELMAN JOSEPH View Filing
form 4 Form 4 — PERCEPTIVE LIFE SCIENCES MASTER FUND LTD View Filing
form 4 Form 4 — PERCEPTIVE ADVISORS LLC View Filing
form 4 Form 4 — EDELMAN JOSEPH View Filing
form 4 Form 4 — PERCEPTIVE LIFE SCIENCES MASTER FUND LTD View Filing
form 4 Form 4 — PERCEPTIVE ADVISORS LLC View Filing
form 4 Form 4 — EDELMAN JOSEPH View Filing
form 4 Form 4 — PERCEPTIVE LIFE SCIENCES MASTER FUND LTD View Filing
form 4 Form 4 — PERCEPTIVE ADVISORS LLC View Filing
edgar index 144 — MeiraGTx Holdings plc View Filing
edgar index 4 — MeiraGTx Holdings plc View Filing
form 4 Form 4 — Forbes Alexandria View Filing
edgar index 4 — MeiraGTx Holdings plc View Filing
edgar index 4 — MeiraGTx Holdings plc View Filing
edgar index 4 — MeiraGTx Holdings plc View Filing
edgar index 4 — MeiraGTx Holdings plc View Filing
edgar index 4 — MeiraGTx Holdings plc View Filing
form 4 Form 4 — Forbes Alexandria View Filing
form 4 Form 4 — Forbes Alexandria View Filing
form 4 Form 4 — Forbes Alexandria View Filing
form 4 Form 4 — Giroux Richard View Filing
form 4 Form 4 — Giroux Richard View Filing
form 4 Form 4 — Giroux Richard View Filing
form 4 Form 4 — Giroux Richard View Filing
form 4 Form 4 — Giroux Richard View Filing
form 4 Form 4 — Naylor Stuart View Filing
form 4 Form 4 — Naylor Stuart View Filing
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form 4 Form 4 — Zeldin Robert K View Filing
form 4 Form 4 — Zeldin Robert K View Filing