Alto Neuroscience (ANRO)

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Alto Neuroscience Inc. is a clinical-stage biotechnology company developing psychiatric medicines with a precision-medicine approach. Rather than treating depression or schizophrenia as uniform conditions, Alto seeks to match drug candidates with patient groups defined by objective measures of brain biology. Its work is built around biomarkers that may include neurocognitive tests, electrophysiology, wearable data, and other brain-based signals intended to identify patients more likely to respond to a specific therapy.

The company’s pipeline is led by multiple clinical-stage programmes, including ALTO-100, ALTO-202, ALTO-207, ALTO-101, and ALTO-300. These candidates are being evaluated initially in major depressive disorder, other depressive conditions, and schizophrenia-related populations. Alto’s strategy reflects a broader shift in neuroscience drug development toward patient stratification, where clinical trials are designed around biologically defined subgroups instead of relying only on symptom-based diagnoses.

Alto is not a commercial-stage pharmaceutical company and its value depends heavily on clinical data, regulatory progress, intellectual property, and its ability to finance development. The company operates in an area with substantial unmet need, as many psychiatric patients do not respond adequately to existing medications and treatment selection often relies on trial and error. By combining drug development with biomarker-led trial design, Alto aims to improve response rates, shorten the path to effective treatment, and create differentiated therapies in markets that have historically been difficult for new medicines to penetrate.

18.85 USD
7.54 USD
+0.14 (+0.75%)
After-hours

Last updated

Market Cap
661.52M
P/E
P/FCF
P/S
Enterprise Value
416.11M
Sector
Health Care
Industry
Pharmaceutical Preparations
Address
650 CASTRO STREET, SUITE 450, MOUNTAIN VIEW, CA, 94041
GlobeNewswire Inc.

ALTO ALERT: Bragar Eagel & Squire, P.C. is Investigating Alto Neuroscience, Inc. on Behalf of Long-Term Stockholders and Encourages Investors to Contact the Firm

07 Oct 2025, 23:05 PM
GlobeNewswire Inc.

Investors who lost money on Alto Neuroscience, Inc.(ANRO) should contact Levi & Korsinsky about pending Class Action - ANRO

19 Sept 2025, 21:49 PM
GlobeNewswire Inc.

ANRO DEADLINE TODAY: ROSEN, A HIGHLY RECOGNIZED LAW FIRM, Encourages Alto Neuroscience, Inc. Investors to Secure Counsel Before Important September 19 Deadline in Securities Class Action - ANRO

19 Sept 2025, 14:50 PM
GlobeNewswire Inc.

ANRO INVESTOR ALERT: Bronstein, Gewirtz & Grossman LLC Announces that Alto Neuroscience, Inc. Investors with Substantial Losses Have Opportunity to Lead Class Action Lawsuit

18 Sept 2025, 21:00 PM
GlobeNewswire Inc.

DEADLINE ALERT: Faruqi & Faruqi, LLP Investigates Claims on Behalf of Investors of Alto Neuroscience

18 Sept 2025, 04:40 AM
GlobeNewswire Inc.

ANRO DEADLINE: ROSEN, NATIONAL TRIAL LAWYERS, Encourages Alto Neuroscience, Inc. Investors to Secure Counsel Before Important September 19 Deadline in Securities Class Action - ANRO

16 Sept 2025, 01:58 AM
GlobeNewswire Inc.

ANRO INVESTOR ALERT: Bronstein, Gewirtz & Grossman LLC Announces that Alto Neuroscience, Inc. Investors with Substantial Losses Have Opportunity to Lead Class Action Lawsuit

14 Sept 2025, 21:00 PM
GlobeNewswire Inc.

ANRO DEADLINE NOTICE: ROSEN, A LEADING LAW FIRM, Encourages Alto Neuroscience, Inc. Investors to Secure Counsel Before Important September 19 Deadline in Securities Class Action - ANRO

12 Sept 2025, 17:41 PM
GlobeNewswire Inc.

Faruqi & Faruqi Reminds Alto Neuroscience Investors of the Pending Class Action Lawsuit with a Lead Plaintiff Deadline of September 19, 2025 - ANRO

12 Sept 2025, 00:18 AM
GlobeNewswire Inc.

Bipolar Disorder Treatment Pipeline Shows Strong Momentum as 20+ Pharma Companies in the Race | DelveInsight

11 Sept 2025, 18:00 PM
GlobeNewswire Inc.

Pomerantz Law Firm Announces the Filing of a Class Action Against Alto Neuroscience, Inc.and Certain Officers – ANRO

10 Sept 2025, 15:00 PM
GlobeNewswire Inc.

ANRO IMPORTANT DEADLINE: ROSEN, A HIGHLY RECOGNIZED LAW FIRM, Encourages Alto Neuroscience, Inc. Investors to Secure Counsel Before Important September 19 Deadline in Securities Class Action - ANRO

09 Sept 2025, 23:51 PM
GlobeNewswire Inc.

ANRO INVESTOR ALERT: Bronstein, Gewirtz & Grossman LLC Announces that Alto Neuroscience, Inc. Investors with Substantial Losses Have Opportunity to Lead Class Action Lawsuit

08 Sept 2025, 21:00 PM
GlobeNewswire Inc.

ANRO DEADLINE: ROSEN, GLOBAL INVESTOR RIGHTS COUNSEL, Encourages Alto Neuroscience, Inc. Investors with Losses in Excess of $100K to Secure Counsel Before Important September 19 Deadline in Securities Class Action - ANRO

05 Sept 2025, 17:30 PM
GlobeNewswire Inc.

PDE4B Inhibitor Market Poised for Strong Growth by 2034 | DelveInsight

03 Sept 2025, 18:00 PM
GlobeNewswire Inc.

ANRO DEADLINE: ROSEN, GLOBAL INVESTOR COUNSEL, Encourages Alto Neuroscience, Inc. Investors with Losses in Excess of $100K to Secure Counsel Before Important Deadline in Securities Class Action - ANRO

03 Sept 2025, 04:36 AM
GlobeNewswire Inc.

Levi & Korsinsky Reminds Shareholders of a Lead Plaintiff Deadline of September 19, 2025 in Alto Neuroscience, Inc. Lawsuit – ANRO

02 Sept 2025, 20:55 PM
GlobeNewswire Inc.

ANRO INVESTOR ALERT: Bronstein, Gewirtz & Grossman LLC Announces that Alto Neuroscience, Inc. Investors with Substantial Losses Have Opportunity to Lead Class Action Lawsuit

01 Sept 2025, 21:00 PM
GlobeNewswire Inc.

Bragar Eagel & Squire, P.C. Reminds Investors of Class Actions Against Neogen, Alto, RxSight, and Replimune and Encourages Investors to Contact the Firm

30 Aug 2025, 13:20 PM
GlobeNewswire Inc.

ANRO DEADLINE: ROSEN, A LEADING INVESTOR RIGHTS LAW FIRM, Encourages Alto Neuroscience, Inc. Investors to Secure Counsel Before Important Deadline in Securities Class Action - ANRO

30 Aug 2025, 12:34 PM
Market Cap
661.52M
Enterprise Value
416.11M
P/E
P/B
2.72
P/S
EV / EBITDA
-5.39
EV / Sales
EPS
-2.12
Dividend Yield
0%
P/FCF
P/CF
Free Cash Flow
-62.86M
ROE
-30.53%
ROA
-26.9%
Debt / Equity
0.08
Current Ratio
20.52
Quick Ratio
20.52
Cash
20.11
Avg Volume
303.78K
Fundamentals Snapshot Price
18.85

Income Statement

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Revenue
Gross profit
Operating income -27.14M -17.06M -14.95M -18.68M -15.68M
EBITDA -26.95M -16.9M -14.79M -18.51M -15.51M
Net income -26.24M -16.18M -14.18M -17.71M -15.17M
Basic EPS -0.8 -0.45 -0.52 -0.65 -0.56
Diluted EPS -0.8 -0.45 -0.52 -0.65 -0.56

Balance Sheet

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Total assets 276.26M 184.69M 147.01M 157.88M 171.92M
Total liabilities 32.89M 33.55M 35.45M 34.47M 32.82M
Total equity 243.37M 151.14M 111.56M 123.41M 139.1M
Cash & equivalents 263.76M 176.48M 137.82M 147.59M 160.75M
Current assets 269.13M 177.72M 139.45M 149.85M 163.52M
Current liabilities 13.12M 11.33M 9.05M 8.13M 7.26M

Cash Flow

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Operating cash flow -27.09M -11.52M -9.92M -13.78M -16.56M
Investing cash flow -556K 0 0 0 -24K
Financing cash flow 114.94M 50.19M 153K 613K 9.13M
Change in cash 87.28M 38.67M -9.77M -13.17M -7.48M
Kind Filing Date Link
edgar index 3 — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
edgar index 8-K — Alto Neuroscience, Inc. View Filing
eight k text 8-K — 8-K View Filing
form 4 Form 4 — Miller Andrew Craig View Filing
edgar index SCHEDULE 13G/A — Alto Neuroscience, Inc. View Filing
edgar index SCHEDULE 13G — Alto Neuroscience, Inc. View Filing
edgar index SCHEDULE 13G/A — Alto Neuroscience, Inc. View Filing
edgar index SCHEDULE 13G/A — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
form 4 Form 4 — Etkin Amit View Filing
edgar index 8-K — Alto Neuroscience, Inc. View Filing
edgar index 10-Q — Alto Neuroscience, Inc. View Filing
edgar index 8-K — Alto Neuroscience, Inc. View Filing
eight k text 8-K — 8-K View Filing
eight k text 8-K — 8-K View Filing
form 4 Form 4 — Dreyfus Andrew View Filing
form 4 Form 4 — Sanchez Ramiro View Filing
form 4 Form 4 — Cox Christopher Nixon View Filing
form 4 Form 4 — York Gwill View Filing
form 4 Form 4 — Manji Husseini View Filing
edgar index EFFECT — Alto Neuroscience, Inc. View Filing
edgar index CORRESP — Alto Neuroscience, Inc. View Filing
edgar index UPLOAD — Alto Neuroscience, Inc. View Filing
edgar index S-3 — Alto Neuroscience, Inc. View Filing
edgar index 8-K — Alto Neuroscience, Inc. View Filing
eight k text 8-K — 8-K View Filing
edgar index DEF 14A — Alto Neuroscience, Inc. View Filing
edgar index DEFA14A — Alto Neuroscience, Inc. View Filing
edgar index ARS — Alto Neuroscience, Inc. View Filing
edgar index S-8 — Alto Neuroscience, Inc. View Filing
edgar index 8-K — Alto Neuroscience, Inc. View Filing
edgar index 8-K — Alto Neuroscience, Inc. View Filing
edgar index 10-K — Alto Neuroscience, Inc. View Filing
eight k text 8-K — 8-K View Filing
eight k text 8-K — 8-K View Filing
ten k section 10-K — business View Filing
ten k section 10-K — mda View Filing
ten k section 10-K — risk_factors View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
form 4 Form 4 — Etkin Amit View Filing
form 4 Form 4 — Smith Nicholas Conrad View Filing
edgar index SCHEDULE 13G/A — Alto Neuroscience, Inc. View Filing
edgar index SCHEDULE 13G — Alto Neuroscience, Inc. View Filing
edgar index SCHEDULE 13G/A — Alto Neuroscience, Inc. View Filing
edgar index SCHEDULE 13G/A — Alto Neuroscience, Inc. View Filing
edgar index SCHEDULE 13G/A — Alto Neuroscience, Inc. View Filing
edgar index SCHEDULE 13G/A — Alto Neuroscience, Inc. View Filing
edgar index SCHEDULE 13G/A — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
form 4 Form 4 — Hanley Jr. Michael Conick View Filing
form 4 Form 4 — Etkin Amit View Filing
form 4 Form 4 — Savitz Adam View Filing
form 4 Form 4 — Smith Nicholas Conrad View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
edgar index 4 — Alto Neuroscience, Inc. View Filing
form 4 Form 4 — Sanchez Ramiro View Filing
form 4 Form 4 — Cox Christopher Nixon View Filing
form 4 Form 4 — York Gwill View Filing
form 4 Form 4 — Manji Husseini View Filing
edgar index EFFECT — Alto Neuroscience, Inc. View Filing
edgar index CORRESP — Alto Neuroscience, Inc. View Filing
edgar index S-3 — Alto Neuroscience, Inc. View Filing
edgar index 8-K — Alto Neuroscience, Inc. View Filing