Tyra Biosciences (TYRA)
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Tyra Biosciences, Inc. is a clinical-stage biotechnology company developing precision medicines based on fibroblast growth factor receptor, or FGFR, biology. FGFR signaling plays an important role in cell growth, development, and tissue repair, but genetic alterations in these pathways can also drive cancers and certain inherited conditions. Tyra focuses on designing small-molecule therapies intended to address defined patient populations where FGFR alterations are central to disease.
The company’s research strategy is built around its proprietary SNAP platform, an internal drug-design system that uses iterative molecular modeling and structure-guided optimization. Through this approach, Tyra seeks to produce candidates with improved potency, selectivity, and tolerability compared with earlier broad FGFR inhibitors, which can be limited by off-target effects, resistance mechanisms, and dosing constraints. Its pipeline includes programs directed at FGFR3, FGFR4/3, and FGFR1/2/3, with assets aimed at targeted oncology as well as genetically defined skeletal conditions.
As a biotechnology stock, Tyra’s value proposition is closely tied to clinical execution, regulatory progress, intellectual property, and the ability to demonstrate meaningful benefit in carefully selected patient groups. The company does not represent a diversified commercial pharmaceutical business; rather, it is focused on advancing investigational therapies through trials and establishing whether its more selective FGFR approach can improve outcomes. This makes its development programs sensitive to trial data, safety findings, enrollment progress, and changes in the competitive landscape for targeted cancer and rare-disease medicines.
Last updated
- Market Cap
- 1.71B
- P/E
- —
- P/FCF
- —
- P/S
- —
- Enterprise Value
- 1.62B
- Sector
- Health Care
- Industry
- Pharmaceutical Preparations
- Address
- 2656 STATE STREET, CARLSBAD, CA, 92008
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- Market Cap
Market cap is the total value of a company's shares, calculated by multiplying the stock price by the number of shares outstanding.
- 1.71B
- Enterprise Value
Enterprise value is the total value of a company, including its market cap, debt, and cash.
- 1.62B
- P/E
P/E ratio compares a company's share price to its earnings per share.
- —
- P/B
P/B ratio compares a company's share price to its book value per share.
- 4.4
- P/S
P/S ratio compares a company's share price to its revenue per share.
- —
- EV / EBITDA
EV/EBITDA measures a company's value compared to its earnings before interest, taxes, depreciation, and amortization.
- -11.39
- EV / Sales
EV/Sales measures a company's value compared to its total revenue.
- —
- EPS
- -2.2
- Dividend Yield
Dividend yield shows how much a company pays in dividends each year compared to its share price.
- 0%
- P/FCF
Price-to-free-cash-flow ratio compares a company's share price to the cash it generates after expenses and investments.
- —
- P/CF
P/CF ratio compares a company's share price to the cash flow it generates from its operations.
- —
- Free Cash Flow
Free cash flow is the cash a company has left after covering operating costs and capital expenses.
- -102.47M
- ROE
ROE measures how effectively a company uses shareholders' equity to generate profit.
- -33.74%
- ROA
ROA measures how effectively a company uses its assets to generate profit.
- -31.74%
- Debt / Equity
Debt-to-equity ratio compares a company's total debt to its shareholders' equity.
- 0
- Current Ratio
Current ratio measures a company's ability to pay short-term debts using its short-term assets.
- 20.49
- Quick Ratio
Quick ratio measures a company's ability to pay short-term debts using cash and other easily available assets.
- 20.49
- Cash
Cash ratio measures a company's ability to cover short-term debts using only cash and cash equivalents.
- 4.41
- Avg Volume
Average volume shows the average number of shares traded over the last 30 trading days, helping indicate liquidity.
- 775.61K
- Fundamentals Snapshot Price
Fundamentals snapshot price is the stock price used when calculating the company's financial ratios and metrics.
- 28.69
Income Statement
| Line Item | 2026 Q1 | 2025 Q4 | 2025 Q3 | 2025 Q2 | 2025 Q1 |
|---|---|---|---|---|---|
| Revenue | — | — | — | — | — |
| Gross profit | — | — | — | — | — |
| Operating income | -42M | -36.52M | -32.94M | -31.45M | -31.85M |
| EBITDA | -41.86M | -36.38M | -32.81M | -31.31M | -31.71M |
| Net income | -39.31M | -33.51M | -29.86M | -28.1M | -28.15M |
| Basic EPS | -0.64 | -0.56 | -0.5 | -0.47 | -0.47 |
| Diluted EPS | -0.64 | -0.56 | -0.5 | -0.47 | -0.47 |
Balance Sheet
| Line Item | 2026 Q1 | 2025 Q4 | 2025 Q3 | 2025 Q2 | 2025 Q1 |
|---|---|---|---|---|---|
| Total assets | 412.04M | 282.61M | 301.85M | 321.5M | 343.48M |
| Total liabilities | 24.47M | 23.43M | 21.34M | 19.35M | 19.94M |
| Total equity | 387.58M | 259.18M | 280.51M | 302.15M | 323.53M |
| Cash & equivalents | 84.96M | 77.39M | 61.95M | 98.49M | 100.72M |
| Current assets | 394.61M | 265.45M | 281.22M | 302.16M | 324.57M |
| Current liabilities | 19.26M | 18.09M | 15.88M | 13.77M | 14.25M |
Cash Flow
| Line Item | 2026 Q1 | 2025 Q4 | 2025 Q3 | 2025 Q2 | 2025 Q1 |
|---|---|---|---|---|---|
| Operating cash flow | -32.57M | -23.62M | -22.38M | -23.68M | -25.46M |
| Investing cash flow | -120.24M | 34.38M | -14.81M | 20.87M | 32.03M |
| Financing cash flow | 160.38M | 4.68M | 647K | 583K | 2.19M |
| Change in cash | 7.57M | 15.44M | -36.54M | -2.23M | 8.76M |
| Kind | Filing | Date | Link |
|---|---|---|---|
| edgar index | 8-K — Tyra Biosciences, Inc. | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 144 — Tyra Biosciences, Inc. | View Filing | |
| form 4 | Form 4 — Rothenberg Stephen Michael | View Filing | |
| form 4 | Form 4 — MORE ROBERT J | View Filing | |
| form 4 | Form 4 — Gulfo Adele M. | View Filing | |
| form 4 | Form 4 — Simson Jake | View Filing | |
| form 4 | Form 4 — Moran Susan | View Filing | |
| form 4 | Form 4 — Verjee Rehan | View Filing | |
| form 4 | Form 4 — RA Capital Nexus Fund, L.P. | View Filing | |
| form 4 | Form 4 — RA CAPITAL MANAGEMENT, L.P. | View Filing | |
| form 4 | Form 4 — Shah Rajeev M. | View Filing | |
| form 4 | Form 4 — Kolchinsky Peter | View Filing | |
| form 4 | Form 4 — RA Capital Healthcare Fund LP | View Filing | |
| edgar index | SCHEDULE 13G/A — Tyra Biosciences, Inc. | View Filing | |
| edgar index | SCHEDULE 13G/A — Tyra Biosciences, Inc. | View Filing | |
| edgar index | SCHEDULE 13G/A — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 8-K — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 10-Q — Tyra Biosciences, Inc. | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| edgar index | SCHEDULE 13G/A — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 144 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| form 4 | Form 4 — Rueb Yuliya | View Filing | |
| form 4 | Form 4 — Rueb Yuliya | View Filing | |
| form 4 | Form 4 — Ashar Bhavesh | View Filing | |
| form 4 | Form 4 — Ashar Bhavesh | View Filing | |
| form 4 | Form 4 — Harris Todd | View Filing | |
| form 4 | Form 4 — Harris Todd | View Filing | |
| form 4 | Form 4 — Fuhrman Alan | View Filing | |
| form 4 | Form 4 — Fuhrman Alan | View Filing | |
| form 4 | Form 4 — Warner Douglas J | View Filing | |
| form 4 | Form 4 — Warner Douglas J | View Filing | |
| edgar index | SCHEDULE 13G/A — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 3 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| form 3 | Form 3 — Dable Habib J | View Filing | |
| edgar index | 8-K — Tyra Biosciences, Inc. | View Filing | |
| edgar index | DEF 14A — Tyra Biosciences, Inc. | View Filing | |
| edgar index | DEFA14A — Tyra Biosciences, Inc. | View Filing | |
| edgar index | ARS — Tyra Biosciences, Inc. | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| form 4 | Form 4 — Dable Habib J | View Filing | |
| edgar index | 144 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | SCHEDULE 13G — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 8-K — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 3 — Tyra Biosciences, Inc. | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| form 3 | Form 3 — Rueb Yuliya | View Filing | |
| form 3 | Form 3 — Rueb Yuliya | View Filing | |
| form 3 | Form 3 — Rueb Yuliya | View Filing | |
| form 3 | Form 3 — Rueb Yuliya | View Filing | |
| form 3 | Form 3 — Rueb Yuliya | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 144 — Tyra Biosciences, Inc. | View Filing | |
| form 4 | Form 4 — KAPLAN GILLA | View Filing | |
| form 4 | Form 4 — KAPLAN GILLA | View Filing | |
| form 4 | Form 4 — KAPLAN GILLA | View Filing | |
| edgar index | 144 — Tyra Biosciences, Inc. | View Filing | |
| form 4 | Form 4 — KAPLAN GILLA | View Filing | |
| form 4 | Form 4 — KAPLAN GILLA | View Filing | |
| form 4 | Form 4 — KAPLAN GILLA | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing | |
| edgar index | 4 — Tyra Biosciences, Inc. | View Filing |