AC Immune (ACIU)
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AC Immune SA is a Swiss clinical-stage biotechnology company developing therapies and diagnostics for neurodegenerative diseases. The company focuses on disorders linked to protein misfolding and aggregation, including Alzheimer’s disease, Parkinson’s disease, and related conditions in which abnormal proteins such as amyloid beta, tau, and alpha-synuclein play a central role.
AC Immune’s strategy is built around precision medicine. It uses proprietary discovery platforms to design small molecules, monoclonal antibodies, vaccines, and diagnostic agents intended to identify, prevent, or treat disease processes before irreversible neurological damage occurs. Its pipeline includes active and passive immunotherapies as well as candidates designed to support earlier and more targeted diagnosis.
The company’s programs include assets such as ACI-24.060, ACI-35.030, ACI-7104.056, semorinemab, and crenezumab, among others. These candidates address different biological targets and stages of neurodegenerative disease, giving AC Immune a diversified research portfolio within a highly challenging therapeutic area. The company also collaborates with larger pharmaceutical partners on selected programs, a common model in biotechnology where clinical development costs and scientific risk are substantial.
As a clinical-stage company, AC Immune does not resemble a mature pharmaceutical business with a broad portfolio of marketed products. Its investment profile is driven by clinical trial progress, biomarker data, regulatory feedback, partnership activity, cash resources, and the evolving scientific understanding of neurodegeneration. The stock offers exposure to one of medicine’s most important unmet needs, but it also carries the development risk typical of companies working on complex brain diseases.
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AC Immune Presents New Phase 1 Data Indicating Higher Uptake of TDP-43 PET Tracer ACI-19626 in Patients with ALS
AC Immune Announces Amendment to Morphomer ® Tau License and Collaboration Agreement with Lilly
AC Immune Positive Interim Phase 2 Data on ACI-7104.056 Support Potential Slowing of Progression of Parkinson’s Disease
AC Immune Reports Third Quarter 2025 Financial Results and Provides a Corporate Update
AC Immune Sharpens Pipeline Focus with Operational Efficiencies Extending Cash Runway
AC Immune Reports Second Quarter 2025 Financial Results and Provides a Corporate Update
AC Immune Reports First Quarter 2025 Financial Results and Provides a Corporate Update
AC Immune Reports Further Positive Interim Results from Phase 2 Trial of ACI-7104.056 Active Immunotherapy in Early Parkinson’s Disease
AC Immune Announces Upcoming Presentations and Industry Symposium on Active Immunotherapies at AD/PD™ 2025
AC Immune Reports Full Year 2024 Financial Results and Provides a Corporate Update
AC Immune Reports Interim Safety Data from Phase 1b/2 ABATE Trial of ACI-24.060 in Down syndrome
The Zacks Analyst Blog Highlights Biogen, Eli Lilly's, Prothena and AC Immune (Revised)
The Zacks Analyst Blog Highlights Biogen, Eli Lilly's, Prothena and AC Immune
Alzheimer's in Focus as FDA Panel Endorses Lilly's Donanemab
AC Immune to Present at the Jefferies Global Healthcare Conference in June 2024
AC Immune Reports First Quarter 2024 Financial Results and Provides a Corporate Update
AC Immune and Takeda Sign Exclusive Option and License Agreement for Active Immunotherapy Targeting Amyloid Beta for Alzheimer’s Disease
AC Immune Reports Full Year 2023 Financial Results and Provides a Corporate Update
AbbVie (ABBV) Announces Appointment of New CEO Robert Michael
Pfizer's (PFE) Ulcerative Colitis Pill Velsipity Gets EU Nod
Income Statement
| Line Item | 2025 Q4 | 2024 Q4 | 2023 Q4 | 2022 Q4 | 2021 Q4 |
|---|---|---|---|---|---|
| Revenue | — | — | — | — | — |
| Gross profit | — | — | — | — | — |
| Operating income | — | — | — | — | — |
| EBITDA | 0 | 0 | 0 | 0 | 0 |
| Net income | — | — | — | — | — |
| Basic EPS | — | — | — | — | — |
| Diluted EPS | — | — | — | — | — |
Balance Sheet
| Line Item | 2025 Q4 | 2024 Q4 | 2023 Q4 | 2022 Q4 | 2021 Q4 |
|---|---|---|---|---|---|
| Total assets | 194.38M | 255.63M | 217.38M | 185.94M | 286.76M |
| Total liabilities | 137.82M | 131.34M | 26.36M | 16.95M | 32.32M |
| Total equity | 56.56M | 124.29M | 191.02M | 168.99M | 254.45M |
| Cash & equivalents | 33.77M | 40.16M | 93.33M | 31.59M | 90.18M |
| Current assets | 40.46M | 47.36M | 119.62M | 37.09M | 95.02M |
| Current liabilities | 119.33M | 111.63M | 16.14M | 11.48M | 21.97M |
Cash Flow
| Line Item | 2025 Q4 | 2024 Q4 | 2023 Q4 | 2022 Q4 | 2021 Q4 |
|---|---|---|---|---|---|
| Operating cash flow | — | — | — | — | — |
| Investing cash flow | — | — | — | — | — |
| Financing cash flow | — | — | — | — | — |
| Change in cash | — | — | — | — | — |
| Kind | Filing | Date | Link |
|---|---|---|---|
| edgar index | 4 — AC Immune SA | View Filing | |
| edgar index | 6-K — AC Immune SA | View Filing | |
| edgar index | 144 — AC Immune SA | View Filing | |
| form 4 | Form 4 — Pfeifer Andrea | View Filing | |
| form 4 | Form 4 — Pfeifer Andrea | View Filing | |
| edgar index | 6-K — AC Immune SA | View Filing | |
| edgar index | 4 — AC Immune SA | View Filing | |
| edgar index | 4/A — AC Immune SA | View Filing | |
| edgar index | 144 — AC Immune SA | View Filing | |
| form 4 | Form 4 — Pfeifer Andrea | View Filing | |
| form 4 | Form 4 — Pfeifer Andrea | View Filing | |
| form 4 | Form 4 — Pfeifer Andrea | View Filing | |
| form 4 | Form 4 — Pfeifer Andrea | View Filing | |
| edgar index | 6-K — AC Immune SA | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| form 3 | Form 3 — Zuegel Martin | View Filing | |
| form 3 | Form 3 — Zuegel Martin | View Filing | |
| form 3 | Form 3 — Zuegel Martin | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — AGUIAR-LUCANDER RENEE | View Filing | |
| form 3 | Form 3 — AGUIAR-LUCANDER RENEE | View Filing | |
| form 3 | Form 3 — AGUIAR-LUCANDER RENEE | View Filing | |
| form 3 | Form 3 — Twyman Roy Ervin | View Filing | |
| form 3 | Form 3 — Twyman Roy Ervin | View Filing | |
| form 3 | Form 3 — Twyman Roy Ervin | View Filing | |
| form 3 | Form 3 — Twyman Roy Ervin | View Filing | |
| form 3 | Form 3 — Twyman Roy Ervin | View Filing | |
| form 3 | Form 3 — Twyman Roy Ervin | View Filing | |
| form 3 | Form 3 — Twyman Roy Ervin | View Filing | |
| form 3 | Form 3 — Twyman Roy Ervin | View Filing | |
| form 3 | Form 3 — Buetler Monika | View Filing | |
| form 3 | Form 3 — Buetler Monika | View Filing | |
| form 3 | Form 3 — Buetler Monika | View Filing | |
| form 3 | Form 3 — Buetler Monika | View Filing | |
| form 3 | Form 3 — Buetler Monika | View Filing | |
| form 3 | Form 3 — Buetler Monika | View Filing | |
| form 3 | Form 3 — Roberts Christopher James | View Filing | |
| form 3 | Form 3 — Roberts Christopher James | View Filing | |
| form 3 | Form 3 — Roberts Christopher James | View Filing | |
| form 3 | Form 3 — Roberts Christopher James | View Filing | |
| form 3 | Form 3 — Roberts Christopher James | View Filing | |
| form 3 | Form 3 — Roberts Christopher James | View Filing | |
| form 3 | Form 3 — Roberts Christopher James | View Filing |