AC Immune (ACIU)

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AC Immune SA is a Swiss clinical-stage biotechnology company developing therapies and diagnostics for neurodegenerative diseases. The company focuses on disorders linked to protein misfolding and aggregation, including Alzheimer’s disease, Parkinson’s disease, and related conditions in which abnormal proteins such as amyloid beta, tau, and alpha-synuclein play a central role.

AC Immune’s strategy is built around precision medicine. It uses proprietary discovery platforms to design small molecules, monoclonal antibodies, vaccines, and diagnostic agents intended to identify, prevent, or treat disease processes before irreversible neurological damage occurs. Its pipeline includes active and passive immunotherapies as well as candidates designed to support earlier and more targeted diagnosis.

The company’s programs include assets such as ACI-24.060, ACI-35.030, ACI-7104.056, semorinemab, and crenezumab, among others. These candidates address different biological targets and stages of neurodegenerative disease, giving AC Immune a diversified research portfolio within a highly challenging therapeutic area. The company also collaborates with larger pharmaceutical partners on selected programs, a common model in biotechnology where clinical development costs and scientific risk are substantial.

As a clinical-stage company, AC Immune does not resemble a mature pharmaceutical business with a broad portfolio of marketed products. Its investment profile is driven by clinical trial progress, biomarker data, regulatory feedback, partnership activity, cash resources, and the evolving scientific understanding of neurodegeneration. The stock offers exposure to one of medicine’s most important unmet needs, but it also carries the development risk typical of companies working on complex brain diseases.

2.90USD
+0.26(+9.85%)

Last updated

Market Cap
$256,521,485
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Market Cap
$256,521,485
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Fundamentals Snapshot Price

Income Statement

Line Item2025 Q42024 Q42023 Q42022 Q42021 Q4
Revenue4.5M30.23M17.6M4.26M0
Cost of revenue00000
Gross profit4.5M30.23M17.6M4.26M0
Operating income-87.35M-57.98M-63.76M-76.63M-79.01M
EBITDA-85.02M-56.34M-61.77M-74.69M-77.11M
Net income-88.77M-56.37M-64.49M-76.53M-73M
Income taxes03.32K11.89K14.06K3K
Interest expense-240.69K-147.24K-209.28K-383.98K-581K
Other operating expenses454.91K-157.2K-1.77M-1.45M-1.18M
Total operating expenses91.85M88.22M81.36M80.89M79.01M
Basic EPS-0.88-0.56-0.76-0.92-0.97
Diluted EPS-0.88-0.56-0.76-0.92-0.97

Balance Sheet

Line Item2025 Q42024 Q42023 Q42022 Q42021 Q4
Total assets194.38M255.63M217.38M185.94M286.76M
Total liabilities137.82M131.34M26.36M16.95M32.32M
Total equity56.56M124.29M191.02M168.99M254.45M
Cash & equivalents33.77M40.16M93.33M31.59M90.18M
Current assets121.88M190.4M148.82M128.09M222.26M
Current liabilities119.33M111.63M16.14M11.48M21.97M
Accounts payable2.61M2.94M2M929K2.2M
Receivables1.23M1.22M18.63M800K1.54M
Inventories00000
Goodwill00000
Long-term debt00000

Cash Flow

Line Item2025 Q42024 Q42023 Q42022 Q42021 Q4
Operating cash flow-87.28M72.89M-71.83M-79.57M-65.69M
Investing cash flow80.07M-116.56M78.06M25.7M-53.66M
Financing cash flow-1.29M-1.24M51.43M-1.46M40.75M
Change in cash-8.49M-44.91M57.65M-55.33M-78.61M
Net income-88.77M-56.37M-64.49M-76.53M-73M
KindFilingDateLink
edgar index6-K — AC Immune SAView Filing
edgar index6-K — AC Immune SAView Filing
edgar index6-K — AC Immune SAView Filing
edgar index6-K — AC Immune SAView Filing
edgar index4 — AC Immune SAView Filing
edgar index4 — AC Immune SAView Filing
edgar index4 — AC Immune SAView Filing
edgar index4 — AC Immune SAView Filing
edgar index4 — AC Immune SAView Filing
edgar index6-K — AC Immune SAView Filing
edgar index6-K — AC Immune SAView Filing
form 4Form 4 — June Carl HowardView Filing
form 4Form 4 — June Carl HowardView Filing
form 4Form 4 — Buetler MonikaView Filing
form 4Form 4 — Buetler MonikaView Filing
form 4Form 4 — Zuegel MartinView Filing
form 4Form 4 — Zuegel MartinView Filing
form 4Form 4 — AGUIAR-LUCANDER RENEEView Filing
form 4Form 4 — AGUIAR-LUCANDER RENEEView Filing
form 4Form 4 — Twyman Roy ErvinView Filing
form 4Form 4 — Twyman Roy ErvinView Filing
edgar index4 — AC Immune SAView Filing
edgar index6-K — AC Immune SAView Filing
edgar index144 — AC Immune SAView Filing
form 4Form 4 — Pfeifer AndreaView Filing
form 4Form 4 — Pfeifer AndreaView Filing
edgar index6-K — AC Immune SAView Filing
edgar index6-K — AC Immune SAView Filing
edgar index6-K — AC Immune SAView Filing
edgar index4 — AC Immune SAView Filing
edgar index4/A — AC Immune SAView Filing
edgar index144 — AC Immune SAView Filing
form 4Form 4 — Pfeifer AndreaView Filing
form 4Form 4 — Pfeifer AndreaView Filing
form 4Form 4 — Pfeifer AndreaView Filing
form 4Form 4 — Pfeifer AndreaView Filing
edgar index6-K — AC Immune SAView Filing
edgar index3 — AC Immune SAView Filing
form 3Form 3 — Zuegel MartinView Filing
form 3Form 3 — Zuegel MartinView Filing
form 3Form 3 — Zuegel MartinView Filing
edgar index3 — AC Immune SAView Filing
form 3Form 3 — Donati PiergiorgioView Filing
form 3Form 3 — Donati PiergiorgioView Filing
form 3Form 3 — Donati PiergiorgioView Filing
form 3Form 3 — Donati PiergiorgioView Filing
form 3Form 3 — Donati PiergiorgioView Filing
form 3Form 3 — Donati PiergiorgioView Filing
form 3Form 3 — Donati PiergiorgioView Filing
form 3Form 3 — Donati PiergiorgioView Filing
form 3Form 3 — Donati PiergiorgioView Filing
form 3Form 3 — Donati PiergiorgioView Filing
edgar index3 — AC Immune SAView Filing
edgar index3 — AC Immune SAView Filing
edgar index3 — AC Immune SAView Filing
edgar index3 — AC Immune SAView Filing
edgar index3 — AC Immune SAView Filing
edgar index3 — AC Immune SAView Filing
form 3Form 3 — June Carl HowardView Filing
form 3Form 3 — June Carl HowardView Filing
form 3Form 3 — June Carl HowardView Filing
form 3Form 3 — June Carl HowardView Filing
form 3Form 3 — June Carl HowardView Filing
form 3Form 3 — June Carl HowardView Filing
form 3Form 3 — June Carl HowardView Filing
form 3Form 3 — Pfeifer AndreaView Filing
form 3Form 3 — Pfeifer AndreaView Filing
form 3Form 3 — Pfeifer AndreaView Filing
form 3Form 3 — Pfeifer AndreaView Filing
form 3Form 3 — Pfeifer AndreaView Filing
form 3Form 3 — Pfeifer AndreaView Filing
form 3Form 3 — Pfeifer AndreaView Filing
form 3Form 3 — Pfeifer AndreaView Filing
form 3Form 3 — Pfeifer AndreaView Filing
form 3Form 3 — AGUIAR-LUCANDER RENEEView Filing