Dyadic International (DYAI)

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Dyadic International, Inc. is a biotechnology platform company built around the production of proteins using its C1 gene expression system. The platform is based on the fungus Thermothelomyces heterothallica and is designed to manufacture enzymes, vaccines, antibodies, and other recombinant proteins efficiently at commercial scale.

The company originally applied its technology to industrial biotechnology, where high-volume enzyme production is important for markets such as biofuels, food processing, animal health, and other industrial applications. Dyadic has licensed aspects of its technology to third parties for non-pharmaceutical uses, including well-known industrial partners. Over time, the company has also directed more attention toward biopharmaceutical applications, where faster and potentially lower-cost protein production can be valuable.

Dyadic’s C1 platform is intended to offer advantages in speed, scalability, and yield compared with some conventional expression systems. In healthcare, those attributes may be relevant for vaccine development, monoclonal antibodies, and other biologic products that require reliable manufacturing. The company typically operates through research collaborations, licensing arrangements, and partnerships rather than by marketing a large portfolio of finished medicines on its own.

For investors, Dyadic represents a platform-technology biotechnology stock rather than a single-product drug developer. Its value depends on whether partners can validate and adopt the C1 system for commercial applications, particularly in regulated pharmaceutical markets where manufacturing standards, safety data, and process consistency are critical.

The company’s distinctive feature is its focus on improving how complex proteins are produced. If its platform gains broader acceptance, Dyadic could play a role in enabling faster or more economical manufacturing across industrial biotech and biologics, though adoption depends on technical performance, regulatory acceptance, and partner execution.

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Last updated

Market Cap
$39,353,799
P/E
P/FCF
P/S
10.34
Enterprise Value
$40,139,955
Sector
Materials
Industry
Biological Products, Except Diagnostic Substances
Address
1044 NORTH U.S. HIGHWAY ONE, JUPITER, FL, 33477
Market Cap
$39,353,799
Enterprise Value
$40,139,955
P/E
P/B
-96.52
P/S
10.34
EV / EBITDA
-5.67
EV / Sales
10.54
EPS
-0.2
Dividend Yield
0%
P/FCF
P/CF
Free Cash Flow
ROE
1,788.36%
ROA
-93.37%
Debt / Equity
-12.34
Current Ratio
2.13
Quick Ratio
2.13
Cash
1.33
Avg Volume
$245,911
Fundamentals Snapshot Price
1.08

Income Statement

Line Item2026 Q12025 Q42025 Q32025 Q22025 Q1
Revenue1.11M565.53K1.16M966.63K393.57K
Cost of revenue791.84K384.61K1.02M613.59K297.66K
Gross profit319.12K180.92K140.61K353.04K95.91K
Operating income-1.91M-1.52M-1.91M-1.71M-2M
EBITDA-1.92M-1.53M-1.92M-1.72M-2.01M
Net income-1.95M-1.57M-1.98M-1.79M-2.03M
Interest expense-109.18K-114.39K-114.11K-113.83K-113.56K
Other operating expenses00000
Total operating expenses2.23M1.71M2.05M2.07M2.09M
Basic EPS-0.05-0.06-0.06-0.06-0.07
Diluted EPS-0.05-0.06-0.06-0.06-0.07

Balance Sheet

Line Item2026 Q12025 Q42025 Q32025 Q22025 Q1
Total assets7.81M9.95M11.67M8.14M7.89M
Total liabilities8.22M8.71M9.07M8.67M6.97M
Total equity-407.73K1.23M2.61M-529.7K923.61K
Cash & equivalents4.25M4.62M5.83M2.14M5.06M
Current assets7.7M9.9M11.55M7.41M7.81M
Current liabilities3.18M3.69M4.05M3.66M1.96M
Accounts payable1.06M852.02K1.21M738.79K448.39K
Receivables1.01M1.13M950.69K750.05K244.93K
Long-term debt5.03M5.03M2.95M3.93M4.99M

Cash Flow

Line Item2026 Q12025 Q42025 Q32025 Q22025 Q1
Operating cash flow-1.96M-1.77M-1.85M-130.02K-1.95M
Investing cash flow1.27M468.16K93.44K-961.62K482.1K
Financing cash flow-14.94M024.25K
Change in cash-697.77K-1.3M3.18M-1.09M-1.44M
Net income-1.95M-1.57M-1.98M-1.79M-2.03M
KindFilingDateLink
edgar index8-K — DYADIC INTERNATIONAL INCView Filing
edgar index4 — DYADIC INTERNATIONAL INCView Filing
eight k text8-K — 8-KView Filing
form 4Form 4 — Francisco Trust under agreement dated February 28, 1996View Filing
form 4Form 4 — Francisco Trust under agreement dated February 28, 1996View Filing
form 4Form 4 — Francisco Trust under agreement dated February 28, 1996View Filing
edgar index144 — DYADIC INTERNATIONAL INCView Filing
edgar indexSCHEDULE 13G/A — DYADIC INTERNATIONAL INCView Filing
edgar index4 — DYADIC INTERNATIONAL INCView Filing
edgar index8-K — DYADIC INTERNATIONAL INCView Filing
eight k text8-K — 8-KView Filing
edgar index8-K — DYADIC INTERNATIONAL INCView Filing
edgar indexDEFA14A — DYADIC INTERNATIONAL INCView Filing
eight k text8-K — 8-KView Filing
edgar index8-K — DYADIC INTERNATIONAL INCView Filing
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edgar index8-K — DYADIC INTERNATIONAL INCView Filing
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edgar index8-K — DYADIC INTERNATIONAL INCView Filing
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edgar indexSCHEDULE 13G — DYADIC INTERNATIONAL INCView Filing
edgar indexSCHEDULE 13G/A — DYADIC INTERNATIONAL INCView Filing
edgar indexPRE 14A — DYADIC INTERNATIONAL INCView Filing
edgar index10-K/A — DYADIC INTERNATIONAL INCView Filing
edgar index8-K — DYADIC INTERNATIONAL INCView Filing
eight k text8-K — 8-KView Filing
edgar index10-K — DYADIC INTERNATIONAL INCView Filing
edgar index8-K — DYADIC INTERNATIONAL INCView Filing
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edgar index424B5 — DYADIC INTERNATIONAL INCView Filing
edgar index8-K — DYADIC INTERNATIONAL INCView Filing
eight k text8-K — 8-KView Filing
edgar indexSCHEDULE 13G/A — DYADIC INTERNATIONAL INCView Filing
edgar index4 — DYADIC INTERNATIONAL INCView Filing
edgar index4 — DYADIC INTERNATIONAL INCView Filing
edgar index4 — DYADIC INTERNATIONAL INCView Filing
edgar index4 — DYADIC INTERNATIONAL INCView Filing
edgar index4 — DYADIC INTERNATIONAL INCView Filing
edgar index4 — DYADIC INTERNATIONAL INCView Filing
edgar index4 — DYADIC INTERNATIONAL INCView Filing
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form 4Form 4 — TCHELET RONENView Filing
form 4Form 4 — TCHELET RONENView Filing
edgar index8-K — DYADIC INTERNATIONAL INCView Filing
edgar index8-K — DYADIC INTERNATIONAL INCView Filing
edgar index4 — DYADIC INTERNATIONAL INCView Filing
eight k text8-K — 8-KView Filing
form 4Form 4 — EMALFARB MARK AView Filing
form 4Form 4 — EMALFARB MARK AView Filing
form 4Form 4 — Francisco Trust under agreement dated February 28, 1996View Filing
edgar indexSCHEDULE 13G/A — DYADIC INTERNATIONAL INCView Filing
edgar index10-Q — DYADIC INTERNATIONAL INCView Filing
edgar index8-K — DYADIC INTERNATIONAL INCView Filing