Xenetic Biosciences (XBIO)

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Xenetic Biosciences, Inc. is a biopharmaceutical company developing therapies for difficult-to-treat cancers, with a particular emphasis on technologies that may enhance the effectiveness of existing oncology treatments. The company’s main scientific focus is DNase-based therapy, which is designed to target neutrophil extracellular traps, commonly known as NETs. These web-like structures are produced by immune cells and have been linked in research to tumour progression, metastasis, inflammation, and resistance to some cancer therapies.

Xenetic’s approach is to use DNase as an adjunctive treatment rather than as a stand-alone replacement for established cancer medicines. By breaking down NETs, its technology is intended to improve the tumour microenvironment and potentially make immunotherapies, chemotherapy, or other treatment modalities more effective. The company is particularly interested in pancreatic cancer, one of the most challenging solid tumours to treat, as well as other locally advanced or metastatic solid cancers.

Its pipeline includes programs identified as XBIO-015 and XBIO-020, which are being advanced for pancreatic carcinoma and broader solid tumour applications. These programs remain part of a development-stage strategy, meaning clinical progress, regulatory feedback, safety data, and financing capacity are central to the company’s outlook.

Xenetic operates in the high-risk, high-potential biotechnology sector, where value is driven by scientific validation and clinical milestones rather than current commercial scale. What differentiates the company is its focus on NETs as a therapeutic target in oncology, an area that sits at the intersection of cancer biology, immunology, and inflammation. For investors, Xenetic represents a specialised immuno-oncology platform company seeking to improve outcomes in cancers where current treatment options remain limited.

3.43 USD
3.10 USD
+0.09 (+2.69%)
After-hours

Last updated

Market Cap
7.86M
P/E
P/FCF
P/S
5.63
Enterprise Value
511.07K
Sector
Health Care
Industry
Pharmaceutical Preparations
Address
945 CONCORD ST., FRAMINGHAM, MA, 01701
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Market Cap
7.86M
Enterprise Value
511.07K
P/E
P/B
1.13
P/S
5.63
EV / EBITDA
-0.12
EV / Sales
0.37
EPS
-0.98
Dividend Yield
0%
P/FCF
P/CF
Free Cash Flow
ROE
-32.14%
ROA
-28.25%
Debt / Equity
0
Current Ratio
7.93
Quick Ratio
7.93
Cash
7.67
Avg Volume
14.39K
Fundamentals Snapshot Price
3.43

Income Statement

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Revenue 806.92K 589.9K 593.26K
Gross profit 806.92K 589.9K 593.26K
Operating income -502.12K -1.39M -1.57M -724.41K -942.41K
EBITDA -502.12K -1.39M -1.57M -724.41K -942.41K
Net income -456.38K -579.08K -509.94K -688.7K -903.14K
Basic EPS -0.2 -0.22 -0.33 -0.45 -0.59
Diluted EPS -0.2 -0.22 -0.33 -0.45 -0.59

Balance Sheet

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Total assets 7.91M 8.36M 5.07M 5.35M 5.79M
Total liabilities 958.24K 968.03K 1.11M 903.43K 667.93K
Total equity 6.95M 7.4M 3.96M 4.45M 5.12M
Cash & equivalents 7.35M 7.88M 4.12M 4.78M 5.16M
Current assets 7.6M 8.05M 5.07M 5.35M 5.48M
Current liabilities 958.24K 968.03K 1.11M 903.43K 667.93K

Cash Flow

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Operating cash flow -536.38K -242.68K -658.25K -383.83K -1M
Investing cash flow
Financing cash flow 4M
Change in cash -536.38K 3.76M -658.25K -383.83K -1M
Kind Filing Date Link
edgar index SCHEDULE 13G — Xenetic Biosciences, Inc. View Filing
edgar index SCHEDULE 13G/A — Xenetic Biosciences, Inc. View Filing
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edgar index SCHEDULE 13G — Xenetic Biosciences, Inc. View Filing
edgar index 8-K — Xenetic Biosciences, Inc. View Filing
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form 4 Form 4 — Borisenko Grigory G. View Filing
form 4 Form 4 — Kornberg Roger D. View Filing
form 4 Form 4 — Dastoor Firdaus J. View Filing
form 4 Form 4 — VINOGRADOV ALEXEY ANDREEVICH View Filing
edgar index 8-K — Xenetic Biosciences, Inc. View Filing
edgar index DEFA14A — Xenetic Biosciences, Inc. View Filing
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edgar index ARS — Xenetic Biosciences, Inc. View Filing
edgar index 424B5 — Xenetic Biosciences, Inc. View Filing
edgar index 8-K — Xenetic Biosciences, Inc. View Filing
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edgar index 8-K — Xenetic Biosciences, Inc. View Filing
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edgar index 8-K — Xenetic Biosciences, Inc. View Filing
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edgar index 10-Q — Xenetic Biosciences, Inc. View Filing
edgar index 10-K/A — Xenetic Biosciences, Inc. View Filing
edgar index 8-K — Xenetic Biosciences, Inc. View Filing
eight k text 8-K — 8-K View Filing
edgar index 8-K — Xenetic Biosciences, Inc. View Filing
edgar index 8-K/A — Xenetic Biosciences, Inc. View Filing
edgar index 10-K — Xenetic Biosciences, Inc. View Filing
ten k section 10-K — business View Filing
ten k section 10-K — risk_factors View Filing
edgar index 8-K — Xenetic Biosciences, Inc. View Filing
edgar index 4 — Xenetic Biosciences, Inc. View Filing
edgar index 4 — Xenetic Biosciences, Inc. View Filing
edgar index 4 — Xenetic Biosciences, Inc. View Filing
edgar index 4 — Xenetic Biosciences, Inc. View Filing
form 4 Form 4 — VINOGRADOV ALEXEY ANDREEVICH View Filing
form 4 Form 4 — Dastoor Firdaus J. View Filing
form 4 Form 4 — Borisenko Grigory G. View Filing
form 4 Form 4 — Kornberg Roger D. View Filing
edgar index 8-K — Xenetic Biosciences, Inc. View Filing
edgar index 10-Q — Xenetic Biosciences, Inc. View Filing
edgar index 8-K — Xenetic Biosciences, Inc. View Filing
edgar index EFFECT — Xenetic Biosciences, Inc. View Filing
edgar index DEF 14A — Xenetic Biosciences, Inc. View Filing
edgar index DEFA14A — Xenetic Biosciences, Inc. View Filing
edgar index ARS — Xenetic Biosciences, Inc. View Filing
edgar index 8-K — Xenetic Biosciences, Inc. View Filing
edgar index CORRESP — Xenetic Biosciences, Inc. View Filing
edgar index UPLOAD — Xenetic Biosciences, Inc. View Filing
edgar index S-3 — Xenetic Biosciences, Inc. View Filing