NextCure (NXTC)

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NextCure, Inc. is a clinical-stage biotechnology company developing targeted medicines for cancer and other serious diseases with high unmet need. Its work is centred on understanding how diseased tissue interacts with the immune system and on designing biologic therapies that can alter those interactions. The company is particularly focused on patients whose tumours fail to respond to existing treatments or progress after standard-of-care therapy.

NextCure’s pipeline includes NC410, a LAIR-2 fusion protein designed to disrupt immune-suppressive signals associated with collagen-rich tumour environments. The candidate is being studied in combination with pembrolizumab, with early clinical activity reported in areas including colorectal and ovarian cancers. The company is also advancing LNCB74, an antibody-drug conjugate directed at B7-H4, a cancer-associated target that is expressed in several tumour types and is viewed as clinically relevant for targeted oncology approaches.

Beyond these lead programmes, NextCure manages a broader portfolio that includes clinical assets such as NC525 and NC318, for which it is seeking partners. It also has earlier-stage programmes outside oncology, including NC605 for chronic bone diseases and NC181 for Alzheimer’s disease. As with many development-stage biopharmaceutical companies, its value is closely tied to clinical trial outcomes, regulatory progress, access to capital, and the ability to form collaborations that can support expensive late-stage development.

3.26 USD
+0.12 (+3.72%)

Last updated

Market Cap
11.38M
P/E
P/FCF
P/S
Enterprise Value
-3.79M
Sector
Health Care
Industry
Pharmaceutical Preparations
Address
9000 VIRGINIA MANOR ROAD, SUITE 200, BELTSVILLE, MD, 20705
GlobeNewswire Inc.

NextCure Provides Business Update

23 Jan 2026, 20:00 PM
GlobeNewswire Inc.

NextCure to Present at 24th Annual Needham Virtual Healthcare Conference

04 Apr 2025, 19:00 PM
GlobeNewswire Inc.

NextCure to Participate in the 36th Annual Piper Sandler Healthcare Conference

26 Nov 2024, 20:00 PM
GlobeNewswire Inc.

NextCure to Present at the H.C. Wainwright 5th Annual Neuro Perspectives Virtual Conference

21 Jun 2024, 04:10 AM
GlobeNewswire Inc.

NextCure to Present Phase 1b Data of NC410 in Combination with Pembrolizumab at ASCO 2024

25 Apr 2024, 04:05 AM
GlobeNewswire Inc.

NextCure and LCB Present Preclinical Data on B7-H4 Antibody Drug Conjugate at AACR 2024

08 Apr 2024, 19:00 PM
GlobeNewswire Inc.

NextCure Appoints Dr. Rakesh Dixit to Scientific Advisory Board

04 Apr 2024, 19:05 PM
GlobeNewswire Inc.

NextCure to Present at 23rd Annual Needham Virtual Healthcare Conference

02 Apr 2024, 19:00 PM
Seeking Alpha

Pyxis Oncology: Data Arriving Later Than Expected, But May Be Worth The Wait

28 Mar 2024, 12:10 PM
GlobeNewswire Inc.

NextCure Provides Business Update and Reports Full Year 2023 Financial Results

21 Mar 2024, 20:55 PM
GlobeNewswire Inc.

NextCure Publishes Preclinical Data Demonstrating Function of FLRT3 as a T Cell Inhibitor in Science Advances

05 Mar 2024, 21:05 PM
GlobeNewswire Inc.

NextCure Presents Preclinical Data on a Novel Therapeutic Candidate Targeting VSTM-1 for the Treatment of Progressive Inflammatory Airway Disorders

19 Jan 2024, 05:05 AM
Zacks Investment Research

Here's Why NextCure, Inc. (NXTC) Looks Ripe for Bottom Fishing

25 Dec 2023, 22:55 PM
GlobeNewswire Inc.

NextCure Publishes Non-Clinical Data Demonstrating Anti-Siglec-15 Treatment Prevented Bone Loss Due to Immobilization from Acute Spinal Cord Injury

21 Dec 2023, 20:05 PM
GlobeNewswire Inc.

NextCure Provides Year-End Clinical Pipeline Updates

14 Dec 2023, 19:45 PM
GlobeNewswire Inc.

NextCure to Present at the 35th Annual Piper Sandler Healthcare Conference

20 Nov 2023, 20:00 PM
GlobeNewswire Inc.

NextCure Publishes Non-Clinical Data Defining the Mechanism of Action for NC525, a Novel LAIR-1 Antibody for AML

16 Nov 2023, 05:05 AM
Zacks Investment Research

All You Need to Know About NextCure, Inc. (NXTC) Rating Upgrade to Buy

08 Nov 2023, 01:00 AM
GlobeNewswire Inc.

NextCure Provides Business Update and Reports Third Quarter 2023 Financial Results

03 Nov 2023, 04:05 AM
GlobeNewswire Inc.

Preclinical Data Demonstrate Anti-Siglec-15 Treatment Reduced Bone Loss and Enhanced Bone Quality in Mice with Moderate-to-Severe Osteogenesis Imperfecta (OI)

17 Oct 2023, 20:05 PM
Market Cap
11.38M
Enterprise Value
-3.79M
P/E
P/B
0.43
P/S
EV / EBITDA
0.07
EV / Sales
EPS
-15.13
Dividend Yield
0%
P/FCF
P/CF
Free Cash Flow
ROE
-204.61%
ROA
-143.94%
Debt / Equity
0
Current Ratio
4.61
Quick Ratio
4.61
Cash
2.2
Avg Volume
88.73K
Fundamentals Snapshot Price
3.15

Income Statement

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Revenue
Gross profit
Operating income -10.11M -9.76M -8.95M -27.29M -11.62M
EBITDA -9.82M -9.39M -8.41M -26.01M -10.97M
Net income -9.8M -9.44M -8.62M -26.81M -10.98M
Basic EPS -1.87 -0.81 -3.22 -11.29 -4.7
Diluted EPS -1.87 -0.81 -3.22 -11.29 -4.7

Balance Sheet

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Total assets 37.98M 50.18M 39.61M 47.69M 67.14M
Total liabilities 11.26M 15.24M 15.97M 16.04M 11.28M
Total equity 26.72M 34.94M 23.65M 29.65M 55.86M
Cash & equivalents 15.17M 25.98M 7.32M 4.89M 21.83M
Current assets 31.74M 43.75M 32.64M 40.02M 58.9M
Current liabilities 6.89M 10.57M 11M 10.78M 5.74M

Cash Flow

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Operating cash flow -13.36M -7.64M -6.27M -22.71M -12.99M
Investing cash flow 1.3M 6M 8.7M 3.76M 7.09M
Financing cash flow 1.25M 20.29M 0 2.02M
Change in cash -10.82M 18.66M 2.43M -16.94M -5.9M
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edgar index 8-K — NextCure, Inc. View Filing
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edgar index 8-K — NextCure, Inc. View Filing
edgar index 10-Q — NextCure, Inc. View Filing
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edgar index EFFECT — NextCure, Inc. View Filing
edgar index CORRESP — NextCure, Inc. View Filing
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edgar index 8-K — NextCure, Inc. View Filing
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edgar index 8-K — NextCure, Inc. View Filing
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