Halozyme Therapeutics (HALO)

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Halozyme Therapeutics, Inc. is a biotechnology company best known for its drug delivery technology, which helps convert certain biologic medicines from intravenous infusion to subcutaneous injection. Its core platform, ENHANZE, is based on recombinant human hyaluronidase PH20, an enzyme designed to temporarily break down hyaluronan under the skin so larger volumes of medicine can be absorbed more quickly. The aim is to reduce treatment time, simplify administration, and improve convenience for patients and healthcare providers.

Halozyme’s business model combines internal scientific expertise with licensing partnerships across the biopharmaceutical industry. Rather than relying only on fully owned drugs, the company works with major pharmaceutical partners that incorporate ENHANZE into approved or investigational therapies. This can generate milestone payments, royalties, and other collaboration revenue as partnered products advance through development and commercialization.

The platform has been applied primarily to complex biologic treatments, including medicines used in oncology, immunology, and other specialty disease areas where patients may otherwise require lengthy clinic-based infusions. By enabling rapid subcutaneous delivery, Halozyme’s technology can become a differentiating feature for established therapies, especially in markets where treatment burden and healthcare system capacity matter.

Halozyme is headquartered in the United States and operates as a specialty biotechnology company with a significant focus on intellectual property, regulatory execution, and partner relationships. Investors typically view the company through the durability of its royalty streams, the breadth of its partnered pipeline, patent life around its technology, and the adoption of subcutaneous formulations in global drug markets. Its distinctive role is not simply drug discovery, but improving how important biologic medicines are delivered.

70.73 USD
66.01 USD
−0.80 (-1.12%)
After-hours

Last updated

Market Cap
8.39B
P/E
24.05
P/FCF
12.57
P/S
5.56
Enterprise Value
10.22B
Sector
Health Care
Industry
Biological Products, Except Diagnostic Substances
Address
12390 EL CAMINO REAL, SAN DIEGO, CA, 92130
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Market Cap
8.39B
Enterprise Value
10.22B
P/E
24.05
P/B
38.2
P/S
5.56
EV / EBITDA
10.8
EV / Sales
6.78
EPS
2.94
Dividend Yield
0%
P/FCF
12.57
P/CF
12.38
Free Cash Flow
667.65M
ROE
158.83%
ROA
13.05%
Debt / Equity
9.76
Current Ratio
2.76
Quick Ratio
2.33
Cash
0.85
Avg Volume
1.79M
Fundamentals Snapshot Price
70.73

Income Statement

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Revenue 376.71M 451.77M 354.26M 325.72M 264.86M
Gross profit 297.47M 373M 299.02M 279.36M 216.46M
Operating income 184.52M -44.19M 217.92M 202.44M 141.54M
EBITDA 218.25M 267.38M 238.34M 222.94M 161.98M
Net income 150.05M -141.59M 175.23M 165.16M 118.1M
Basic EPS 1.27 -1.16 1.49 1.36 0.96
Diluted EPS 1.22 -1.12 1.43 1.33 0.93

Balance Sheet

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Total assets 2.67B 2.53B 2.22B 2.05B 2.2B
Total liabilities 2.45B 2.48B 1.72B 1.72B 1.71B
Total equity 219.64M 48.81M 503.92M 332.75M 482.27M
Cash & equivalents 309.75M 133.82M 419.67M 61.86M 176.33M
Current assets 1B 825.21M 1.33B 1.12B 1.26B
Current liabilities 363.21M 177.09M 837.23M 134.28M 150.38M

Cash Flow

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Operating cash flow 180.08M 219.03M 178.6M 99.71M 154.22M
Investing cash flow -2.88M -741.79M 201.61M 84.79M -90.42M
Financing cash flow -1.61M 239.52M -22.4M -298.97M -3.32M
Change in cash 175.59M -283.24M 357.8M -114.47M 60.48M
Kind Filing Date Link
edgar index 4 — HALOZYME THERAPEUTICS, INC. View Filing
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edgar index 8-K — HALOZYME THERAPEUTICS, INC. View Filing
edgar index 10-Q — HALOZYME THERAPEUTICS, INC. View Filing
edgar index 144 — HALOZYME THERAPEUTICS, INC. View Filing
eight k text 8-K — 8-K View Filing
form 4 Form 4 — Torley Helen View Filing
form 4 Form 4 — Torley Helen View Filing
form 4 Form 4 — Torley Helen View Filing
form 4 Form 4 — Torley Helen View Filing
form 4 Form 4 — Torley Helen View Filing
edgar index 8-K — HALOZYME THERAPEUTICS, INC. View Filing
edgar index 4 — HALOZYME THERAPEUTICS, INC. View Filing
edgar index 4 — HALOZYME THERAPEUTICS, INC. View Filing
edgar index 4 — HALOZYME THERAPEUTICS, INC. View Filing
edgar index 4 — HALOZYME THERAPEUTICS, INC. View Filing
edgar index 4 — HALOZYME THERAPEUTICS, INC. View Filing
edgar index 4 — HALOZYME THERAPEUTICS, INC. View Filing
eight k text 8-K — 8-K View Filing
edgar index 4 — HALOZYME THERAPEUTICS, INC. View Filing
form 4 Form 4 — Connaughton Bernadette View Filing
form 4 Form 4 — Connaughton Bernadette View Filing
form 4 Form 4 — DUNCAN BARBARA GAYLE View Filing
form 4 Form 4 — DUNCAN BARBARA GAYLE View Filing
form 4 Form 4 — Henderson Jeffrey William View Filing
form 4 Form 4 — Henderson Jeffrey William View Filing
form 4 Form 4 — Lang James Paul View Filing
form 4 Form 4 — Lang James Paul View Filing
form 4 Form 4 — Krishnan Mahesh View Filing
form 4 Form 4 — Krishnan Mahesh View Filing
form 4 Form 4 — Posard Matthew L. View Filing
form 4 Form 4 — Posard Matthew L. View Filing
edgar index 144 — HALOZYME THERAPEUTICS, INC. View Filing
form 4 Form 4 — Connaughton Bernadette View Filing
edgar index 8-K — HALOZYME THERAPEUTICS, INC. View Filing
eight k text 8-K — 8-K View Filing
edgar index 4 — HALOZYME THERAPEUTICS, INC. View Filing
form 4 Form 4 — Torley Helen View Filing
form 4 Form 4 — Torley Helen View Filing
form 4 Form 4 — Torley Helen View Filing
form 4 Form 4 — Torley Helen View Filing
edgar index 4 — HALOZYME THERAPEUTICS, INC. View Filing
edgar index 4 — HALOZYME THERAPEUTICS, INC. View Filing
form 4 Form 4 — Torley Helen View Filing