AC Immune (ACIU)
NasdaqMarket Closed
AC Immune SA is a Swiss clinical-stage biotechnology company developing therapies and diagnostics for neurodegenerative diseases. The company focuses on disorders linked to protein misfolding and aggregation, including Alzheimer’s disease, Parkinson’s disease, and related conditions in which abnormal proteins such as amyloid beta, tau, and alpha-synuclein play a central role.
AC Immune’s strategy is built around precision medicine. It uses proprietary discovery platforms to design small molecules, monoclonal antibodies, vaccines, and diagnostic agents intended to identify, prevent, or treat disease processes before irreversible neurological damage occurs. Its pipeline includes active and passive immunotherapies as well as candidates designed to support earlier and more targeted diagnosis.
The company’s programs include assets such as ACI-24.060, ACI-35.030, ACI-7104.056, semorinemab, and crenezumab, among others. These candidates address different biological targets and stages of neurodegenerative disease, giving AC Immune a diversified research portfolio within a highly challenging therapeutic area. The company also collaborates with larger pharmaceutical partners on selected programs, a common model in biotechnology where clinical development costs and scientific risk are substantial.
As a clinical-stage company, AC Immune does not resemble a mature pharmaceutical business with a broad portfolio of marketed products. Its investment profile is driven by clinical trial progress, biomarker data, regulatory feedback, partnership activity, cash resources, and the evolving scientific understanding of neurodegeneration. The stock offers exposure to one of medicine’s most important unmet needs, but it also carries the development risk typical of companies working on complex brain diseases.
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- Market Cap
- $262,487,100
- P/E
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- P/FCF
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- P/S
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- Enterprise Value
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- Sector
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- Industry
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- Address
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Real Parkinson’s Disease Hope from Jupiter Neurosciences
AC Immune Secures FDA Fast Track For ACI-7104 In Parkinson's; Stock Up
AC Immune Presents New Phase 1 Data Indicating Higher Uptake of TDP-43 PET Tracer ACI-19626 in Patients with ALS
AC Immune Announces Amendment to Morphomer ® Tau License and Collaboration Agreement with Lilly
AC Immune Positive Interim Phase 2 Data on ACI-7104.056 Support Potential Slowing of Progression of Parkinson’s Disease
AC Immune Reports Third Quarter 2025 Financial Results and Provides a Corporate Update
AC Immune Sharpens Pipeline Focus with Operational Efficiencies Extending Cash Runway
- Market Cap
Market cap is the total value of a company's shares, calculated by multiplying the stock price by the number of shares outstanding.
- $262,487,100
- Enterprise Value
Enterprise value is the total value of a company, including its market cap, debt, and cash.
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- P/E
P/E ratio compares a company's share price to its earnings per share.
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- P/B
P/B ratio compares a company's share price to its book value per share.
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- P/S
P/S ratio compares a company's share price to its revenue per share.
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- EV / EBITDA
EV/EBITDA measures a company's value compared to its earnings before interest, taxes, depreciation, and amortization.
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- EV / Sales
EV/Sales measures a company's value compared to its total revenue.
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- EPS
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- Dividend Yield
Dividend yield shows how much a company pays in dividends each year compared to its share price.
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- P/FCF
Price-to-free-cash-flow ratio compares a company's share price to the cash it generates after expenses and investments.
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- P/CF
P/CF ratio compares a company's share price to the cash flow it generates from its operations.
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- Free Cash Flow
Free cash flow is the cash a company has left after covering operating costs and capital expenses.
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- ROE
ROE measures how effectively a company uses shareholders' equity to generate profit.
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- ROA
ROA measures how effectively a company uses its assets to generate profit.
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- Debt / Equity
Debt-to-equity ratio compares a company's total debt to its shareholders' equity.
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- Current Ratio
Current ratio measures a company's ability to pay short-term debts using its short-term assets.
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- Quick Ratio
Quick ratio measures a company's ability to pay short-term debts using cash and other easily available assets.
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- Cash
Cash ratio measures a company's ability to cover short-term debts using only cash and cash equivalents.
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- Avg Volume
Average volume shows the average number of shares traded over the last 30 trading days, helping indicate liquidity.
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- Fundamentals Snapshot Price
Fundamentals snapshot price is the stock price used when calculating the company's financial ratios and metrics.
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Income Statement
| Line Item | 2025 Q4 | 2024 Q4 | 2023 Q4 | 2022 Q4 | 2021 Q4 |
|---|---|---|---|---|---|
| Revenue | 4.5M | 30.23M | 17.6M | 4.26M | 0 |
| Cost of revenue | 0 | 0 | 0 | 0 | 0 |
| Gross profit | 4.5M | 30.23M | 17.6M | 4.26M | 0 |
| Operating income | -87.35M | -57.98M | -63.76M | -76.63M | -79.01M |
| EBITDA | -85.02M | -56.34M | -61.77M | -74.69M | -77.11M |
| Net income | -88.77M | -56.37M | -64.49M | -76.53M | -73M |
| Income taxes | 0 | 3.32K | 11.89K | 14.06K | 3K |
| Interest expense | -240.69K | -147.24K | -209.28K | -383.98K | -581K |
| Other operating expenses | 454.91K | -157.2K | -1.77M | -1.45M | -1.18M |
| Total operating expenses | 91.85M | 88.22M | 81.36M | 80.89M | 79.01M |
| Basic EPS | -0.88 | -0.56 | -0.76 | -0.92 | -0.97 |
| Diluted EPS | -0.88 | -0.56 | -0.76 | -0.92 | -0.97 |
Balance Sheet
| Line Item | 2025 Q4 | 2024 Q4 | 2023 Q4 | 2022 Q4 | 2021 Q4 |
|---|---|---|---|---|---|
| Total assets | 194.38M | 255.63M | 217.38M | 185.94M | 286.76M |
| Total liabilities | 137.82M | 131.34M | 26.36M | 16.95M | 32.32M |
| Total equity | 56.56M | 124.29M | 191.02M | 168.99M | 254.45M |
| Cash & equivalents | 33.77M | 40.16M | 93.33M | 31.59M | 90.18M |
| Current assets | 121.88M | 190.4M | 148.82M | 128.09M | 222.26M |
| Current liabilities | 119.33M | 111.63M | 16.14M | 11.48M | 21.97M |
| Accounts payable | 2.61M | 2.94M | 2M | 929K | 2.2M |
| Receivables | 1.23M | 1.22M | 18.63M | 800K | 1.54M |
| Inventories | 0 | 0 | 0 | 0 | 0 |
| Goodwill | 0 | 0 | 0 | 0 | 0 |
| Long-term debt | 0 | 0 | 0 | 0 | 0 |
Cash Flow
| Line Item | 2025 Q4 | 2024 Q4 | 2023 Q4 | 2022 Q4 | 2021 Q4 |
|---|---|---|---|---|---|
| Operating cash flow | -87.28M | 72.89M | -71.83M | -79.57M | -65.69M |
| Investing cash flow | 80.07M | -116.56M | 78.06M | 25.7M | -53.66M |
| Financing cash flow | -1.29M | -1.24M | 51.43M | -1.46M | 40.75M |
| Change in cash | -8.49M | -44.91M | 57.65M | -55.33M | -78.61M |
| Net income | -88.77M | -56.37M | -64.49M | -76.53M | -73M |
| Kind | Filing | Date | Link |
|---|---|---|---|
| edgar index | 6-K — AC Immune SA | View Filing | |
| edgar index | 6-K — AC Immune SA | View Filing | |
| edgar index | 6-K — AC Immune SA | View Filing | |
| edgar index | 6-K — AC Immune SA | View Filing | |
| edgar index | 4 — AC Immune SA | View Filing | |
| edgar index | 4 — AC Immune SA | View Filing | |
| edgar index | 4 — AC Immune SA | View Filing | |
| edgar index | 4 — AC Immune SA | View Filing | |
| edgar index | 4 — AC Immune SA | View Filing | |
| edgar index | 6-K — AC Immune SA | View Filing | |
| edgar index | 6-K — AC Immune SA | View Filing | |
| form 4 | Form 4 — June Carl Howard | View Filing | |
| form 4 | Form 4 — June Carl Howard | View Filing | |
| form 4 | Form 4 — Buetler Monika | View Filing | |
| form 4 | Form 4 — Buetler Monika | View Filing | |
| form 4 | Form 4 — Zuegel Martin | View Filing | |
| form 4 | Form 4 — Zuegel Martin | View Filing | |
| form 4 | Form 4 — AGUIAR-LUCANDER RENEE | View Filing | |
| form 4 | Form 4 — AGUIAR-LUCANDER RENEE | View Filing | |
| form 4 | Form 4 — Twyman Roy Ervin | View Filing | |
| form 4 | Form 4 — Twyman Roy Ervin | View Filing | |
| edgar index | 4 — AC Immune SA | View Filing | |
| edgar index | 6-K — AC Immune SA | View Filing | |
| edgar index | 144 — AC Immune SA | View Filing | |
| form 4 | Form 4 — Pfeifer Andrea | View Filing | |
| form 4 | Form 4 — Pfeifer Andrea | View Filing | |
| edgar index | 6-K — AC Immune SA | View Filing | |
| edgar index | 6-K — AC Immune SA | View Filing | |
| edgar index | 6-K — AC Immune SA | View Filing | |
| edgar index | 4 — AC Immune SA | View Filing | |
| edgar index | 4/A — AC Immune SA | View Filing | |
| edgar index | 144 — AC Immune SA | View Filing | |
| form 4 | Form 4 — Pfeifer Andrea | View Filing | |
| form 4 | Form 4 — Pfeifer Andrea | View Filing | |
| form 4 | Form 4 — Pfeifer Andrea | View Filing | |
| form 4 | Form 4 — Pfeifer Andrea | View Filing | |
| edgar index | 6-K — AC Immune SA | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| form 3 | Form 3 — Zuegel Martin | View Filing | |
| form 3 | Form 3 — Zuegel Martin | View Filing | |
| form 3 | Form 3 — Zuegel Martin | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| form 3 | Form 3 — Donati Piergiorgio | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| edgar index | 3 — AC Immune SA | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — June Carl Howard | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — Pfeifer Andrea | View Filing | |
| form 3 | Form 3 — AGUIAR-LUCANDER RENEE | View Filing |