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Dyadic International (DYAI)

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Dyadic International, Inc. is a biotechnology platform company built around the production of proteins using its C1 gene expression system. The platform is based on the fungus Thermothelomyces heterothallica and is designed to manufacture enzymes, vaccines, antibodies, and other recombinant proteins efficiently at commercial scale.

The company originally applied its technology to industrial biotechnology, where high-volume enzyme production is important for markets such as biofuels, food processing, animal health, and other industrial applications. Dyadic has licensed aspects of its technology to third parties for non-pharmaceutical uses, including well-known industrial partners. Over time, the company has also directed more attention toward biopharmaceutical applications, where faster and potentially lower-cost protein production can be valuable.

Dyadic’s C1 platform is intended to offer advantages in speed, scalability, and yield compared with some conventional expression systems. In healthcare, those attributes may be relevant for vaccine development, monoclonal antibodies, and other biologic products that require reliable manufacturing. The company typically operates through research collaborations, licensing arrangements, and partnerships rather than by marketing a large portfolio of finished medicines on its own.

For investors, Dyadic represents a platform-technology biotechnology stock rather than a single-product drug developer. Its value depends on whether partners can validate and adopt the C1 system for commercial applications, particularly in regulated pharmaceutical markets where manufacturing standards, safety data, and process consistency are critical.

The company’s distinctive feature is its focus on improving how complex proteins are produced. If its platform gains broader acceptance, Dyadic could play a role in enabling faster or more economical manufacturing across industrial biotech and biologics, though adoption depends on technical performance, regulatory acceptance, and partner execution.

0.69 USD
+0.02 (+3.20%)

Last updated

Market Cap
25.51M
P/E
P/FCF
P/S
6.7
Enterprise Value
26.29M
Sector
Health Care
Industry
Biological Products, Except Diagnostic Substances
Address
1044 NORTH U.S. HIGHWAY ONE, JUPITER, FL, 33477
GlobeNewswire Inc.

Skyline Corporate Communications Group, LLC Announces Dyadic Applied BioSolutions to Deliver a Live Presentation at the Skyline Signature Series™ on Wednesday, May 27 at 12:00 PM ET

May 21, 2026, 15:45 PM
GlobeNewswire Inc.

Dyadic to Report First Quarter 2025 Financial Results on Wednesday, May 14, 2025

May 01, 2025, 15:00 PM
GlobeNewswire Inc.

Dyadic Expands Global Presence with Participation in Key Industry Events

Oct 09, 2024, 08:00 AM
GlobeNewswire Inc.

Dyadic International, Inc. and Proliant Health and Biologicals announce Recombinant Albumin Development and Commercialization Partnership

Jun 28, 2024, 08:30 AM
GlobeNewswire Inc.

Dyadic to Attend Industry and Investor Events in May

May 08, 2024, 08:30 AM
GlobeNewswire Inc.

Dyadic to Report First Quarter 2024 Financial Results on Tuesday, May 14, 2024

Apr 30, 2024, 16:30 PM
GlobeNewswire Inc.

Dyadic Reports 2023 Full Year Results and Recent Company Progress

Mar 28, 2024, 16:00 PM
GlobeNewswire Inc.

Dyadic Announces Change in Board and Management Leadership Roles

Mar 28, 2024, 08:30 AM
GlobeNewswire Inc.

Dyadic Announces Publication of C1 Monoclonal Antibody in Nonhuman Primate Study in Nature Communications

Mar 26, 2024, 08:30 AM
GlobeNewswire Inc.

Dyadic to Attend Future Food Tech Event March 21 – 22, 2024 in San Francisco, California

Mar 21, 2024, 08:30 AM
GlobeNewswire Inc.

Dyadic to Report Full Year 2023 Financial Results and Host Conference call on Thursday, March 28, 2024

Mar 14, 2024, 16:30 PM
GlobeNewswire Inc.

CORRECTION – Dyadic Announces Closing of Private Placement of $6.0 Million Convertible Notes to Accelerate Near-Term Revenue Growth and Commercialization

Mar 11, 2024, 09:57 AM
GlobeNewswire Inc.

Dyadic Announces Closing of Private Placement of $6.0 Million Convertible Notes to Accelerate Near-Term Revenue Growth and Commercialization

Mar 11, 2024, 08:30 AM
GlobeNewswire Inc.

Dyadic to Attend Industry Events in March

Mar 01, 2024, 08:30 AM
GlobeNewswire Inc.

Dyadic Announces Strategic Partnership Agreement to Develop Affordable Rabies Prophylactics and Vaccines Using its Proprietary C1 Cell Microbial Protein Production Platform

Feb 28, 2024, 08:30 AM
GlobeNewswire Inc.

Dyadic Advances Collaboration with Israel Institute for Biological Research (IIBR) Targeting Bio-Threats and Emerging Disease Solutions

Feb 23, 2024, 02:00 AM
GlobeNewswire Inc.

Dyadic Advances Collaboration with Israel Institute for Biological Research (IIBR) Targeting Bio-Threats and Emerging Disease Solutions

Feb 21, 2024, 08:30 AM
GlobeNewswire Inc.

Dyadic and Cygnus Technologies Announce Partnership To Provide C1 HCP ELISA Assay to Enhance Quality Assurance in Biomanufacturing

Feb 13, 2024, 08:30 AM
GlobeNewswire Inc.

Dyadic Announces Research and Development Collaboration Agreement with Global Biopharmaceutical Company

Feb 06, 2024, 08:30 AM
GlobeNewswire Inc.

Dyadic to Attend J.P. Morgan 42nd Annual Healthcare Conference

Jan 02, 2024, 08:30 AM
Market Cap
25.51M
Enterprise Value
26.29M
P/E
P/B
-62.56
P/S
6.7
EV / EBITDA
-3.71
EV / Sales
6.91
EPS
-0.2
Dividend Yield
0%
P/FCF
P/CF
Free Cash Flow
ROE
1,788.36%
ROA
-93.37%
Debt / Equity
-12.34
Current Ratio
2.13
Quick Ratio
2.13
Cash
1.33
Avg Volume
415.89K
Fundamentals Snapshot Price
0.7

Income Statement

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Revenue 1.11M 565.53K 1.16M 966.63K 393.57K
Gross profit 319.12K 180.92K 140.61K 353.04K 95.91K
Operating income -1.91M -1.52M -1.91M -1.71M -2M
EBITDA -1.92M -1.53M -1.92M -1.72M -2.01M
Net income -1.95M -1.57M -1.98M -1.79M -2.03M
Basic EPS -0.05 -0.06 -0.06 -0.06 -0.07
Diluted EPS -0.05 -0.06 -0.06 -0.06 -0.07

Balance Sheet

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Total assets 7.81M 9.95M 11.67M 8.14M 7.89M
Total liabilities 8.22M 8.71M 9.07M 8.67M 6.97M
Total equity -407.73K 1.23M 2.61M -529.7K 923.61K
Cash & equivalents 4.25M 4.62M 5.83M 2.14M 5.06M
Current assets 6.79M 8.67M 10.22M 5.82M 7.81M
Current liabilities 3.18M 3.69M 4.05M 3.66M 1.96M

Cash Flow

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Operating cash flow -1.96M -1.77M -1.85M -130.02K -1.95M
Investing cash flow 1.27M 468.16K 93.44K -961.62K 482.1K
Financing cash flow -1 4.94M 0 24.25K
Change in cash -697.77K -1.3M 3.18M -1.09M -1.44M
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edgar index SCHEDULE 13G/A — DYADIC INTERNATIONAL INC View Filing
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edgar index SCHEDULE 13G/A — DYADIC INTERNATIONAL INC View Filing
edgar index 10-Q — DYADIC INTERNATIONAL INC View Filing
edgar index 8-K — DYADIC INTERNATIONAL INC View Filing
edgar index 4 — DYADIC INTERNATIONAL INC View Filing
edgar index 8-K — DYADIC INTERNATIONAL INC View Filing
form 4 Form 4 — Hazelton Joseph P View Filing
edgar index 424B5 — DYADIC INTERNATIONAL INC View Filing
edgar index 424B5 — DYADIC INTERNATIONAL INC View Filing
edgar index 8-K — DYADIC INTERNATIONAL INC View Filing
edgar index 8-K — DYADIC INTERNATIONAL INC View Filing