MeiraGTx Holdings (MGTX)
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MeiraGTx Holdings plc is a clinical-stage genetic medicines company developing gene-based therapies for serious disorders where existing treatment options are limited. The company focuses on targeted delivery of therapeutic genes and gene-regulation technologies, with programmes spanning ophthalmology, neurodegenerative disease and salivary gland disorders. Its areas of development include radiation-induced xerostomia, Parkinson’s disease and AIPL1-associated retinal dystrophy, among other inherited or acquired conditions.
A defining feature of MeiraGTx is its vertically integrated operating model. The company has built internal capabilities across vector design, process development, GMP viral vector manufacturing, plasmid production and quality control. This infrastructure is intended to give the business greater control over product quality, scale-up and supply as candidates progress from investigational studies toward potential commercial use.
MeiraGTx also works with proprietary technology platforms designed to improve the performance and safety profile of genetic medicines. Its viral vector engineering efforts aim to optimise delivery to specific tissues, while its riboswitch-based gene regulation platform is designed to control the level of therapeutic protein expression after administration. These tools may help reduce dosing requirements or improve the therapeutic window of gene therapies.
The company operates across the United States, the United Kingdom and the European Union, giving it access to major research, regulatory and clinical development markets. As a listed biotechnology stock, MeiraGTx is tied to the progress of its clinical pipeline, manufacturing execution, regulatory milestones and the broader investor appetite for genetic medicine companies.
Last updated
- Market Cap
- 869.6M
- P/E
- —
- P/FCF
- 209.29
- P/S
- 10.9
- Enterprise Value
- 872.76M
- Sector
- Health Care
- Industry
- Biological Products, Except Diagnostic Substances
- Address
- 655 THIRD AVENUE, NEW YORK, NY, 10017
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MeiraGTx Announces Poster Presentation at the 2023 American Society of Gene and Cell Therapy (ASGCT) Spotlight on Immuno-Oncology
MeiraGTx Announces its Wholly-Owned Gene Therapy Manufacturing Facility in Shannon, Ireland has Received Commercial MIA Authorization for QC Testing
MeiraGTx Announces Positive Clinical Data from the AQUAx Phase 1 Clinical Study of AAV2-hAQP1 for the Treatment of Grade 2/3 Radiation-Induced Xerostomia
MeiraGTx to Present 12-month Data from All Cohorts of the Completed Phase 1 AQUAx Clinical Study and an Update on the Company’s Recently Initiated Phase 2 Study of AAV-hAQP1 for the Treatment of Grade 2/3 Radiation-Induced Xerostomia on Tuesday, June 27, 2023
Does MeiraGTx Holdings PLC (MGTX) Have the Potential to Rally 320.9% as Wall Street Analysts Expect?
- Market Cap
Market cap is the total value of a company's shares, calculated by multiplying the stock price by the number of shares outstanding.
- 869.6M
- Enterprise Value
Enterprise value is the total value of a company, including its market cap, debt, and cash.
- 872.76M
- P/E
P/E ratio compares a company's share price to its earnings per share.
- —
- P/B
P/B ratio compares a company's share price to its book value per share.
- -14.96
- P/S
P/S ratio compares a company's share price to its revenue per share.
- 10.9
- EV / EBITDA
EV/EBITDA measures a company's value compared to its earnings before interest, taxes, depreciation, and amortization.
- -9.41
- EV / Sales
EV/Sales measures a company's value compared to its total revenue.
- 10.94
- EPS
- -1.3
- Dividend Yield
Dividend yield shows how much a company pays in dividends each year compared to its share price.
- 0%
- P/FCF
Price-to-free-cash-flow ratio compares a company's share price to the cash it generates after expenses and investments.
- 209.29
- P/CF
P/CF ratio compares a company's share price to the cash flow it generates from its operations.
- 105.04
- Free Cash Flow
Free cash flow is the cash a company has left after covering operating costs and capital expenses.
- 4.16M
- ROE
ROE measures how effectively a company uses shareholders' equity to generate profit.
- 207.35%
- ROA
ROA measures how effectively a company uses its assets to generate profit.
- -49.27%
- Debt / Equity
Debt-to-equity ratio compares a company's total debt to its shareholders' equity.
- -1.29
- Current Ratio
Current ratio measures a company's ability to pay short-term debts using its short-term assets.
- 0.55
- Quick Ratio
Quick ratio measures a company's ability to pay short-term debts using cash and other easily available assets.
- 0.55
- Cash
Cash ratio measures a company's ability to cover short-term debts using only cash and cash equivalents.
- 0.41
- Avg Volume
Average volume shows the average number of shares traded over the last 30 trading days, helping indicate liquidity.
- 762.13K
- Fundamentals Snapshot Price
Fundamentals snapshot price is the stock price used when calculating the company's financial ratios and metrics.
- 9.39
Income Statement
| Line Item | 2026 Q1 | 2025 Q4 | 2025 Q3 | 2025 Q2 | 2025 Q1 |
|---|---|---|---|---|---|
| Revenue | 293K | 75.36M | 410K | 3.69M | 1.93M |
| Gross profit | 293K | 75.36M | 410K | 3.69M | 1.93M |
| Operating income | -40.82M | 26.47M | -46.05M | -44.79M | -41.6M |
| EBITDA | -37.81M | 29.59M | -42.9M | -41.6M | -38.52M |
| Net income | -46.31M | 15.09M | -50.51M | -38.8M | -39.98M |
| Basic EPS | -0.57 | 0.19 | -0.62 | -0.48 | -0.51 |
| Diluted EPS | -0.57 | 0.19 | -0.62 | -0.48 | -0.51 |
Balance Sheet
| Line Item | 2026 Q1 | 2025 Q4 | 2025 Q3 | 2025 Q2 | 2025 Q1 |
|---|---|---|---|---|---|
| Total assets | 244.66M | 244.43M | 189.47M | 198.72M | 224.01M |
| Total liabilities | 302.79M | 250.22M | 230.03M | 195.76M | 190.92M |
| Total equity | -58.13M | -5.79M | -40.56M | 2.96M | 33.1M |
| Cash & equivalents | 71.54M | 65.93M | 14.84M | 32.17M | 66.52M |
| Current assets | 96.2M | 91.76M | 34.17M | 47.08M | 79.89M |
| Current liabilities | 176.13M | 122.56M | 152.92M | 53.44M | 52.37M |
Cash Flow
| Line Item | 2026 Q1 | 2025 Q4 | 2025 Q3 | 2025 Q2 | 2025 Q1 |
|---|---|---|---|---|---|
| Operating cash flow | 17.81M | 46.63M | -12.22M | -43.95M | -36.83M |
| Investing cash flow | -2.26M | -1.09M | -547K | -761K | -1.71M |
| Financing cash flow | -10.11M | 5.33M | -219K | 5.45M | 1.71M |
| Change in cash | 5.44M | 50.87M | -12.98M | -39.26M | -36.83M |
| Kind | Filing | Date | Link |
|---|---|---|---|
| edgar index | 4 — MeiraGTx Holdings plc | View Filing | |
| form 4 | Form 4 — Giroux Richard | View Filing | |
| form 4 | Form 4 — Giroux Richard | View Filing | |
| form 4 | Form 4 — Giroux Richard | View Filing | |
| edgar index | 144 — MeiraGTx Holdings plc | View Filing | |
| edgar index | 4 — MeiraGTx Holdings plc | View Filing | |
| form 4 | Form 4 — Forbes Alexandria | View Filing | |
| edgar index | 8-K — MeiraGTx Holdings plc | View Filing | |
| edgar index | 10-Q — MeiraGTx Holdings plc | View Filing | |
| edgar index | 3 — MeiraGTx Holdings plc | View Filing | |
| edgar index | 4 — MeiraGTx Holdings plc | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| edgar index | SCHEDULE 13G/A — MeiraGTx Holdings plc | View Filing | |
| form 4 | Form 4 — Fleck Penny Renee | View Filing | |
| form 4 | Form 4 — Fleck Penny Renee | View Filing | |
| edgar index | 4/A — MeiraGTx Holdings plc | View Filing | |
| edgar index | 8-K — MeiraGTx Holdings plc | View Filing | |
| edgar index | SCHEDULE 13D/A — MeiraGTx Holdings plc | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| edgar index | 4 — MeiraGTx Holdings plc | View Filing | |
| edgar index | 144 — MeiraGTx Holdings plc | View Filing | |
| edgar index | 4 — MeiraGTx Holdings plc | View Filing | |
| form 4 | Form 4 — Giroux Richard | View Filing | |
| form 4 | Form 4 — Giroux Richard | View Filing | |
| form 4 | Form 4 — Giroux Richard | View Filing | |
| form 4 | Form 4 — PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | View Filing | |
| form 4 | Form 4 — PERCEPTIVE ADVISORS LLC | View Filing | |
| form 4 | Form 4 — EDELMAN JOSEPH | View Filing | |
| edgar index | 8-K — MeiraGTx Holdings plc | View Filing | |
| edgar index | 8-K — MeiraGTx Holdings plc | View Filing | |
| edgar index | 8-K — MeiraGTx Holdings plc | View Filing | |
| edgar index | 424B5 — MeiraGTx Holdings plc | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| edgar index | 4 — MeiraGTx Holdings plc | View Filing | |
| edgar index | 144 — MeiraGTx Holdings plc | View Filing | |
| form 4 | Form 4 — Naylor Stuart | View Filing | |
| edgar index | 10-K — MeiraGTx Holdings plc | View Filing | |
| edgar index | 8-K — MeiraGTx Holdings plc | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| form 4 | Form 4 — EDELMAN JOSEPH | View Filing | |
| form 4 | Form 4 — PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | View Filing | |
| form 4 | Form 4 — PERCEPTIVE ADVISORS LLC | View Filing | |
| form 4 | Form 4 — EDELMAN JOSEPH | View Filing | |
| form 4 | Form 4 — PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | View Filing | |
| form 4 | Form 4 — PERCEPTIVE ADVISORS LLC | View Filing | |
| form 4 | Form 4 — EDELMAN JOSEPH | View Filing | |
| form 4 | Form 4 — PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | View Filing | |
| form 4 | Form 4 — PERCEPTIVE ADVISORS LLC | View Filing | |
| form 4 | Form 4 — EDELMAN JOSEPH | View Filing | |
| form 4 | Form 4 — PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | View Filing | |
| form 4 | Form 4 — PERCEPTIVE ADVISORS LLC | View Filing | |
| edgar index | 144 — MeiraGTx Holdings plc | View Filing | |
| edgar index | 4 — MeiraGTx Holdings plc | View Filing | |
| form 4 | Form 4 — Forbes Alexandria | View Filing | |
| edgar index | 4 — MeiraGTx Holdings plc | View Filing | |
| edgar index | 4 — MeiraGTx Holdings plc | View Filing | |
| edgar index | 4 — MeiraGTx Holdings plc | View Filing | |
| edgar index | 4 — MeiraGTx Holdings plc | View Filing | |
| edgar index | 4 — MeiraGTx Holdings plc | View Filing | |
| form 4 | Form 4 — Forbes Alexandria | View Filing | |
| form 4 | Form 4 — Forbes Alexandria | View Filing | |
| form 4 | Form 4 — Forbes Alexandria | View Filing | |
| form 4 | Form 4 — Giroux Richard | View Filing | |
| form 4 | Form 4 — Giroux Richard | View Filing | |
| form 4 | Form 4 — Giroux Richard | View Filing | |
| form 4 | Form 4 — Giroux Richard | View Filing | |
| form 4 | Form 4 — Giroux Richard | View Filing | |
| form 4 | Form 4 — Naylor Stuart | View Filing | |
| form 4 | Form 4 — Naylor Stuart | View Filing | |
| form 4 | Form 4 — Naylor Stuart | View Filing | |
| form 4 | Form 4 — Zeldin Robert K | View Filing | |
| form 4 | Form 4 — Zeldin Robert K | View Filing | |
| form 4 | Form 4 — Zeldin Robert K | View Filing |