Pacific Biosciences of California (PACB)
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Pacific Biosciences of California, Inc., commonly known as PacBio, is a life sciences technology company that develops advanced DNA sequencing systems for research and clinical applications. The company’s platforms are designed to help scientists read genetic material with high accuracy and detail, supporting work in human genetics, rare disease research, oncology, infectious disease, agriculture, and other areas where genomic information is important.
PacBio is best known for long-read sequencing, a method that can capture extended stretches of DNA and reveal genetic variation that may be difficult to detect with shorter-read technologies. Long reads can be useful for identifying structural variants, resolving complex regions of the genome, assembling new genomes, and studying epigenetic signals. The company’s instruments, consumables, software, and analytical tools form an integrated workflow for laboratories that need high-quality genetic analysis.
The business operates as a single reportable segment centered on the development, manufacture, and sale of sequencing platforms and related products. Revenue comes from instrument placements, recurring consumables used in sequencing runs, service, and support. Its customer base includes academic institutions, government research centers, clinical laboratories, pharmaceutical companies, and agricultural genomics organizations.
PacBio competes in a rapidly evolving genomics market where performance, cost per sample, throughput, accuracy, and ease of use are critical. Investors typically follow the company’s adoption rates, new product launches, consumables pull-through, gross margin trends, cash position, and the pace at which long-read sequencing gains broader use in research and translational medicine.
Last updated
- Market Cap
- 490.75M
- P/E
- —
- P/FCF
- —
- P/S
- 3.07
- Enterprise Value
- 1.08B
- Sector
- —
- Industry
- Laboratory Analytical Instruments
- Address
- 1305 O'BRIEN DRIVE, MENLO PARK, CA, 94025
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- Market Cap
Market cap is the total value of a company's shares, calculated by multiplying the stock price by the number of shares outstanding.
- 490.75M
- Enterprise Value
Enterprise value is the total value of a company, including its market cap, debt, and cash.
- 1.08B
- P/E
P/E ratio compares a company's share price to its earnings per share.
- —
- P/B
P/B ratio compares a company's share price to its book value per share.
- 207.42
- P/S
P/S ratio compares a company's share price to its revenue per share.
- 3.07
- EV / EBITDA
EV/EBITDA measures a company's value compared to its earnings before interest, taxes, depreciation, and amortization.
- -7.21
- EV / Sales
EV/Sales measures a company's value compared to its total revenue.
- 6.74
- EPS
- -0.41
- Dividend Yield
Dividend yield shows how much a company pays in dividends each year compared to its share price.
- 0%
- P/FCF
Price-to-free-cash-flow ratio compares a company's share price to the cash it generates after expenses and investments.
- —
- P/CF
P/CF ratio compares a company's share price to the cash flow it generates from its operations.
- —
- Free Cash Flow
Free cash flow is the cash a company has left after covering operating costs and capital expenses.
- -134.91M
- ROE
ROE measures how effectively a company uses shareholders' equity to generate profit.
- -5,434.32%
- ROA
ROA measures how effectively a company uses its assets to generate profit.
- -16.43%
- Debt / Equity
Debt-to-equity ratio compares a company's total debt to its shareholders' equity.
- 272.23
- Current Ratio
Current ratio measures a company's ability to pay short-term debts using its short-term assets.
- 5.65
- Quick Ratio
Quick ratio measures a company's ability to pay short-term debts using cash and other easily available assets.
- 4.87
- Cash
Cash ratio measures a company's ability to cover short-term debts using only cash and cash equivalents.
- 0.86
- Avg Volume
Average volume shows the average number of shares traded over the last 30 trading days, helping indicate liquidity.
- 6.57M
- Fundamentals Snapshot Price
Fundamentals snapshot price is the stock price used when calculating the company's financial ratios and metrics.
- 1.58
Income Statement
| Line Item | 2026 Q1 | 2025 Q4 | 2025 Q3 | 2025 Q2 | 2025 Q1 |
|---|---|---|---|---|---|
| Revenue | 37.18M | 44.65M | 38.44M | 39.77M | 37.15M |
| Gross profit | 12.84M | 16.57M | 15.9M | 14.68M | -1.37M |
| Operating income | -54.15M | -41.2M | -38.88M | -44.85M | -447.63M |
| EBITDA | -35.53M | -37.44M | -35.4M | -41.18M | -61.11M |
| Net income | -8.28M | -40.37M | -38M | -41.93M | -426.08M |
| Basic EPS | -0.03 | -0.13 | -0.13 | -0.14 | -1.44 |
| Diluted EPS | -0.03 | -0.13 | -0.13 | -0.14 | -1.44 |
Balance Sheet
| Line Item | 2026 Q1 | 2025 Q4 | 2025 Q3 | 2025 Q2 | 2025 Q1 |
|---|---|---|---|---|---|
| Total assets | 782.37M | 784.08M | 803.16M | 825.47M | 860.79M |
| Total liabilities | 780M | 778.73M | 767.07M | 763.98M | 769.15M |
| Total equity | 2.37M | 5.35M | 36.09M | 61.49M | 91.64M |
| Cash & equivalents | 56.27M | 63.71M | 56.47M | 54.8M | 58.51M |
| Current assets | 369.5M | 375.03M | 393.94M | 413.1M | 444.23M |
| Current liabilities | 65.36M | 72.83M | 63.21M | 59.75M | 66.6M |
Cash Flow
| Line Item | 2026 Q1 | 2025 Q4 | 2025 Q3 | 2025 Q2 | 2025 Q1 |
|---|---|---|---|---|---|
| Operating cash flow | -44.69M | -19.07M | -18.71M | -48.08M | -44.06M |
| Investing cash flow | 35.86M | 26.03M | 18.9M | 25.28M | 45.23M |
| Financing cash flow | 1.44M | 0 | 1.47M | 18.7M | 1.96M |
| Change in cash | -7.4M | 6.96M | 1.66M | -4.09M | 3.14M |
| Kind | Filing | Date | Link |
|---|---|---|---|
| edgar index | SD — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | DEFA14A — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 10-Q — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 8-K — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| edgar index | DEF 14A — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | DEFA14A — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | ARS — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| form 4 | Form 4 — Gibson Christopher | View Filing | |
| form 4 | Form 4 — Gibson Christopher | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 144 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| form 4 | Form 4 — Gibson James R II | View Filing | |
| edgar index | SCHEDULE 13G/A — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 8-K — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| edgar index | 8-K — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 3 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 144 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 144 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| form 4 | Form 4 — Farmer Michele | View Filing | |
| form 4 | Form 4 — Van Oene Mark | View Filing | |
| form 4 | Form 4 — HENRY CHRISTIAN O | View Filing | |
| form 4 | Form 4 — Gibson Christopher | View Filing | |
| form 4 | Form 4 — Gibson Christopher | View Filing | |
| form 4 | Form 4 — HENRY CHRISTIAN O | View Filing | |
| form 4 | Form 4 — HENRY CHRISTIAN O | View Filing | |
| form 4 | Form 4 — Van Oene Mark | View Filing | |
| form 4 | Form 4 — Van Oene Mark | View Filing | |
| form 4 | Form 4 — Gibson James R II | View Filing | |
| form 4 | Form 4 — Gibson James R II | View Filing | |
| form 4 | Form 4 — Farmer Michele | View Filing | |
| form 4 | Form 4 — Farmer Michele | View Filing | |
| edgar index | S-3ASR — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 10-K — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | S-8 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| ten k section | 10-K — business | View Filing | |
| ten k section | 10-K — mda | View Filing | |
| ten k section | 10-K — risk_factors | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| form 4 | Form 4 — Farmer Michele | View Filing | |
| form 4 | Form 4 — HENRY CHRISTIAN O | View Filing | |
| form 4 | Form 4 — Van Oene Mark | View Filing | |
| edgar index | 144 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 144 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| form 4 | Form 4 — Farmer Michele | View Filing | |
| form 4 | Form 4 — HENRY CHRISTIAN O | View Filing | |
| form 4 | Form 4 — Van Oene Mark | View Filing | |
| edgar index | 8-K — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| edgar index | SCHEDULE 13G/A — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 8-K — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| edgar index | 8-K — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| edgar index | 8-K — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| edgar index | SCHEDULE 13G/A — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 10-Q — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 8-K — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| eight k text | 8-K — 8-K | View Filing | |
| edgar index | SCHEDULE 13G/A — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing | |
| edgar index | 4 — PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | View Filing |