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XBI vs IBB: what’s a better way to play the biotech space?

XBI vs IBB: what’s a better way to play the biotech space?
Wajeeh Khan
Oct 30, 2022, 16:49 PM
  • Bryn Talkington explains why she's bullish on biotech stocks right now.
  • She prefers "XBI" over "IBB" for a more refined exposure to biotech.
  • The SPDR S&P Biotech ETF is currently up over 30% versus mid-June.

Biotech will continue to outperform the benchmark since the U.S. economy is currently in late-cycle expansion, says Bryn Talkington. She’s a Managing Partner at Requisite Capital Management.

Biotech is still trading at a discount

“Continue” because that subsector of healthcare has already done better than the broader market over the past four months. But Talkington is convinced the romance with biotech stocks is not over just yet.

Unlike the other two, biotech gives you exposure to growth as well, making it an even better pick for investing in late-cycle, she added.

“XBI” – the SPDR S&P Biotech ETF is currently up over 30% versus mid-June.

How to play the biotech space?

Another broadly talked-about exchange-traded fund to play the biotech space is “IBB” – the iShares Biotechnology ETF.

But Talkington prefers XBI over IBB for a more refined exposure to this space. On CNBC’s “Closing Bell: Overtime”, she said:

In comparison, the iShares Biotechnology ETF focuses more on the larger cap names. It is also not a “pure-play” and exposes investors, to a certain extent, to the pharmaceutical space as well.