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GRI Bio (GRI)

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GRI Bio, Inc. is a clinical-stage biotechnology company developing therapies for serious diseases in which the immune system is abnormally activated. The company focuses on inflammatory, fibrotic, and autoimmune conditions, where dysregulated immune responses can drive tissue damage and long-term disease progression. Its strategy centres on modulating Natural Killer T, or NKT, cells, a class of immune cells that can influence both inflammatory signalling and immune balance.

GRI Bio’s lead programme is GRI-0621, an oral small-molecule candidate designed as a dual agonist of retinoic acid receptor beta and gamma. The company is evaluating the compound for its ability to inhibit human type 1 NKT cell activity and help restore immune homeostasis. The active approach is related to tazarotene, a synthetic retinoid best known for dermatology uses such as psoriasis and acne, but GRI Bio is pursuing systemic applications in diseases where immune-driven inflammation and fibrosis are central features.

The company is also advancing GRI-0803, an oral candidate intended to activate type 2 NKT cells. This programme is aimed at autoimmune disorders and reflects GRI Bio’s broader interest in selectively adjusting immune pathways rather than broadly suppressing immunity. As a development-stage biotech, GRI Bio’s value is closely tied to preclinical and clinical progress, regulatory milestones, safety data, and its ability to secure capital or partnerships. Investors typically view the stock as a high-risk life sciences exposure, with potential upside linked to successful validation of its NKT cell-focused platform.

2.11 USD
+0.14 (+6.97%)

Last updated

Market Cap
3.56M
P/E
P/FCF
P/S
Enterprise Value
-7.49M
Sector
Health Care
Industry
Pharmaceutical Preparations
Address
2223 AVENIDA DE LA PLAYA, LA JOLLA, CA, 92037
GlobeNewswire Inc.

GRI Bio CEO, Marc Hertz, Participates in Virtual Investor “What This Means” Segment

Jul 31, 2025, 13:50 PM
GlobeNewswire Inc.

Windtree Announces the Addition of Leanne Kelly to Its Board of Directors

Jan 13, 2025, 08:00 AM
GlobeNewswire Inc.

GRI Bio Announces European Patent Office Issued a Decision to Grant Notice for Patent Covering GRI-0803 and Its Library of 500+ Proprietary Compounds

Dec 23, 2024, 09:00 AM
GlobeNewswire Inc.

GRI Bio Announces Exercise of Warrants

Oct 21, 2024, 17:35 PM
GlobeNewswire Inc.

GRI Bio (NASDAQ: GRI) to Participate in the Virtual Investor Lunch Break Series - GlobeNewswire

Jul 15, 2024, 09:07 AM
GlobeNewswire Inc.

GRI Bio (NASDAQ: GRI) Participates in Virtual Investor “What This Means” Segment - GlobeNewswire

Jul 11, 2024, 09:20 AM
GlobeNewswire Inc.

GRI Bio Announces Publication of Positive Preclinical Data from Lead Program GRI-0621 in the American Journal of Respiratory and Critical Care Medicine

Jul 02, 2024, 09:05 AM
GlobeNewswire Inc.

GRI Bio to Present at the 8th Annual IPF Summit

Jul 01, 2024, 08:45 AM
GlobeNewswire Inc.

GRI Bio Announces Closing of $4.0 Million Public Offering

Jun 28, 2024, 16:05 PM
GlobeNewswire Inc.

GRI Bio Announces Korea Patent Granted for Proprietary Natural Killer T (NKT) Cell Modulators

Jun 27, 2024, 09:00 AM
GlobeNewswire Inc.

GRI Bio Announces Reverse Stock Split

Jun 14, 2024, 08:05 AM
GlobeNewswire Inc.

GRI Bio (NASDAQ: GRI) Participates in Virtual Investor “What This Means” Segment Highlighting Positive Preclinical Data from Idiopathic Pulmonary Fibrosis (IPF) and Systemic Lupus Erythematosus (SLE) Programs

May 22, 2024, 09:15 AM
GlobeNewswire Inc.

GRI Bio Presents Positive Preclinical Data from Pipeline of NKT Cell Modulators in Development for the Treatment of Systemic Lupus Erythematosus (SLE)

May 21, 2024, 08:35 AM
GlobeNewswire Inc.

GRI Bio Presents Positive Preclinical Data Demonstrating Lead Program GRI-0621 Reduces the Important Inflammatory and Fibrotic Drivers in Idiopathic Pulmonary Fibrosis (IPF)

May 20, 2024, 08:45 AM
GlobeNewswire Inc.

GRI Bio to Present at Alliance Global Partner’s 2024 Healthcare Company Showcase

May 14, 2024, 09:05 AM
GlobeNewswire Inc.

GRI Bio Reports First Quarter 2024 Financial Results and Provides Corporate Update

May 13, 2024, 08:00 AM
GlobeNewswire Inc.

GRI Bio Announces Abstracts Accepted for Presentation at the 14th International Congress on Autoimmunity

Apr 29, 2024, 08:45 AM
GlobeNewswire Inc.

GRI Bio to Present at LIVE! with Webull Corporate Connect: Virtual Biotech Investment Webinar

Apr 25, 2024, 09:15 AM
GlobeNewswire Inc.

GRI Bio Expands Intellectual Property Protection for Proprietary Natural Killer T (NKT) Cell Modulators with Issuance of Korea Patent

Apr 16, 2024, 08:35 AM
GlobeNewswire Inc.

GRI Bio Announces Abstract Accepted for Poster Presentation at the 2024 American Thoracic Society International Conference

Apr 08, 2024, 08:35 AM
Market Cap
3.56M
Enterprise Value
-7.49M
P/E
P/B
0.34
P/S
EV / EBITDA
0.69
EV / Sales
EPS
-6.16
Dividend Yield
0%
P/FCF
P/CF
Free Cash Flow
-12.14M
ROE
-103.44%
ROA
-96.2%
Debt / Equity
0
Current Ratio
14.21
Quick Ratio
14.21
Cash
13.91
Avg Volume
37.47K
Fundamentals Snapshot Price
2.01

Income Statement

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Revenue
Gross profit
Operating income -2M -2.66M -3.37M -2.9M -3.05M
EBITDA -2M -2.66M -3.36M -2.9M -3.05M
Net income -2M -2.66M -3.36M -2.89M -3.05M
Basic EPS -1.61 -116.61 -1.28 -1.31 -162.3
Diluted EPS -1.61 -116.61 -1.28 -1.31 -162.3

Balance Sheet

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Total assets 11.34M 8.67M 4.78M 5.68M 4.04M
Total liabilities 794K 2.66M 2.79M 2.35M 2.84M
Total equity 10.55M 6.01M 1.99M 3.32M 1.21M
Cash & equivalents 11.05M 8.23M 4.06M 5.12M 3.28M
Current assets 11.28M 8.59M 4.7M 5.58M 3.93M
Current liabilities 794K 2.64M 2.76M 2.31M 2.78M

Cash Flow

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Operating cash flow -3.69M -2.97M -2.31M -3.17M -1.74M
Investing cash flow -3K
Financing cash flow 6.5M 7.15M 1.25M 5.01M -11K
Change in cash 2.82M 4.17M -1.07M 1.84M -1.75M
Kind Filing Date Link
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edgar index CORRESP — GRI Bio, Inc. View Filing
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form 4 Form 4 — Kelly Leanne View Filing
form 4 Form 4 — Szekeres David Leslie View Filing
form 4 Form 4 — Rongen Roelof View Filing
form 4 Form 4 — SIMPSON CAMILLA V View Filing
form 4 Form 4 — Baker David Charles View Filing
form 4 Form 4 — Hertz Walter Marc View Filing
form 4 Form 4 — Chaturvedi Vipin View Filing
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form 4 Form 4 — Kelly Leanne View Filing
form 4 Form 4 — SIMPSON CAMILLA V View Filing
form 4 Form 4 — Chaturvedi Vipin View Filing