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Tyra Biosciences (TYRA)

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Tyra Biosciences, Inc. is a clinical-stage biotechnology company developing precision medicines based on fibroblast growth factor receptor, or FGFR, biology. FGFR signaling plays an important role in cell growth, development, and tissue repair, but genetic alterations in these pathways can also drive cancers and certain inherited conditions. Tyra focuses on designing small-molecule therapies intended to address defined patient populations where FGFR alterations are central to disease.

The company’s research strategy is built around its proprietary SNAP platform, an internal drug-design system that uses iterative molecular modeling and structure-guided optimization. Through this approach, Tyra seeks to produce candidates with improved potency, selectivity, and tolerability compared with earlier broad FGFR inhibitors, which can be limited by off-target effects, resistance mechanisms, and dosing constraints. Its pipeline includes programs directed at FGFR3, FGFR4/3, and FGFR1/2/3, with assets aimed at targeted oncology as well as genetically defined skeletal conditions.

As a biotechnology stock, Tyra’s value proposition is closely tied to clinical execution, regulatory progress, intellectual property, and the ability to demonstrate meaningful benefit in carefully selected patient groups. The company does not represent a diversified commercial pharmaceutical business; rather, it is focused on advancing investigational therapies through trials and establishing whether its more selective FGFR approach can improve outcomes. This makes its development programs sensitive to trial data, safety findings, enrollment progress, and changes in the competitive landscape for targeted cancer and rare-disease medicines.

27.19 USD
−1.32 (-4.60%)

Last updated

Market Cap
1.71B
P/E
P/FCF
P/S
Enterprise Value
1.62B
Sector
Health Care
Industry
Pharmaceutical Preparations
Address
2656 STATE STREET, CARLSBAD, CA, 92008
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Market Cap
1.71B
Enterprise Value
1.62B
P/E
P/B
4.4
P/S
EV / EBITDA
-11.39
EV / Sales
EPS
-2.2
Dividend Yield
0%
P/FCF
P/CF
Free Cash Flow
-102.47M
ROE
-33.74%
ROA
-31.74%
Debt / Equity
0
Current Ratio
20.49
Quick Ratio
20.49
Cash
4.41
Avg Volume
775.61K
Fundamentals Snapshot Price
28.69

Income Statement

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Revenue
Gross profit
Operating income -42M -36.52M -32.94M -31.45M -31.85M
EBITDA -41.86M -36.38M -32.81M -31.31M -31.71M
Net income -39.31M -33.51M -29.86M -28.1M -28.15M
Basic EPS -0.64 -0.56 -0.5 -0.47 -0.47
Diluted EPS -0.64 -0.56 -0.5 -0.47 -0.47

Balance Sheet

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Total assets 412.04M 282.61M 301.85M 321.5M 343.48M
Total liabilities 24.47M 23.43M 21.34M 19.35M 19.94M
Total equity 387.58M 259.18M 280.51M 302.15M 323.53M
Cash & equivalents 84.96M 77.39M 61.95M 98.49M 100.72M
Current assets 394.61M 265.45M 281.22M 302.16M 324.57M
Current liabilities 19.26M 18.09M 15.88M 13.77M 14.25M

Cash Flow

Line Item 2026 Q1 2025 Q4 2025 Q3 2025 Q2 2025 Q1
Operating cash flow -32.57M -23.62M -22.38M -23.68M -25.46M
Investing cash flow -120.24M 34.38M -14.81M 20.87M 32.03M
Financing cash flow 160.38M 4.68M 647K 583K 2.19M
Change in cash 7.57M 15.44M -36.54M -2.23M 8.76M
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edgar index 3 — Tyra Biosciences, Inc. View Filing
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